Opioid Analgesics

Question 1

Delta and orphan receptors are similar, and their effects are not really _________________

Answer 1

Understood

Question 2

What three effects does a sigma opioid receptor produce

Answer 2

1. Hallucination
2. Whining
3. Mydriasis

Question 3

Other drugs (phencyclidines) can also attach to sigma receptors. What is a common phencyclidine that would produce the same effects as opioids on the sigma receptors

Answer 3

Ketamine

Question 4

The opioid analgesic morphine, is a class ________ drug that attaches to the ___________ receptors. Is it an agonist, antagonist, or both

Answer 4

Class 2
Mu
Agonist

Question 5

Bc morphine is an opioid/ pure Mu agonist, it causes the following 4 effects

Answer 5

1. Respiratory depression
2. Euphoria
3. Analgesic
4. Dependence

Question 6

Morphine is often used for what two purposes

Answer 6

Severe pain
Pre anesthesia

Question 7

What are three side effects of morphine “red”

Answer 7

1. Respiratory depression
2. Emesis
3. Dysphoria (cats and horses)

Question 8

______________ is a synthetic opioid that is 5-7x potent than morphine, like morphine, it is a class 2, _______ agonist used for severe pain and preanesthesia

Answer 8

Hydromorphone
Mu

Question 9

Like morphine, hydromorphone causes respiratory depression, but less _________________

Answer 9

Emesis

Question 10

_______________ is considered the standard of opioids, and therefore drugs are often compared to it

Answer 10

Morphine