Positive Inotropes Flashcards
This drug category is a positive inotrope from foxglove plants, that has a very narrow safety margin and would only be used in vet medicine by extra label
Cardiac glycosides (digoxin)
The catecholamine positive inotropes increase cardiac output, inotropy, chronotropy, and BP. These effects decrease cardiac _______________ bc of increased ______________ consumption
Efficiency
Oxygen consumption
The inotropic catecholamines target ____________ receptors
Adrenergic
Which catecholamine inotrope targets alpha and beta receptors causing bronchiole dilation, positive inotrope, and increased blood GLUCOSE
Epinephrine
Which catecholamine inotrope is a norepinephrine pre cursor that targets alpha 1 and beta 1 receptors causing positive chronotropy, positive inotrope, and increased BP
Dopamine
Which catecholamine inotrope targets beta 1 receptors, causing positive chronotropy and positvie inotrope
Dobutamine
Vet vs human epinephrine concentrations
Vet: 1 mg/ mL
Human: 0.1 mg/ mL
Anti arrhythmic drugs are divided into four classifications. Class l is a….
that decreases the propagation of impulses
Cell membrane stabilizer
What are three class l (membrane stabilizers) anti arrhythmics
- Lidocaine
- Mexiletine
- Procainamide
Class ll anti arrhythmic drugs are ____________ _____________ and cause negative inotropy and negative chronotropy
Beta blockers/ antagonists