Distribution

Question 1

Another way to say “volume of distribution”

Answer 1

The volume in the body the drug is distributed into

Question 2

What will a larger volume in the body, do to the concentration of the drug in the blood

Answer 2

Decrease concentration/ insufficient levels for action

Question 3

Bc younger animals have greater water composition, they have increased…..

Answer 3

Volume of distribution

Question 4

Bc younger animals have greater water composition, they have decreased….

Answer 4

Concentration in blood

Question 5

Metabolism/ biotransformation means…

Answer 5

Alteration of the drug into metabolites

Question 6

Oxidation is ______________ electrons

Answer 6

Loosing (OIL rig)

Question 7

Reduction is ____________ electrons

Answer 7

Gaining (oil RIG)

Question 8

Drugs are biotransformed into metabolites that can be either ____________, ___________, or ____________

Answer 8

Active, Inactive, or Toxic

Question 9

Microsomal enzymes help _____________ drugs. Without a good ______________ P450 system, the drugs will not be metabolized

Answer 9

Metabolize
Cytochrome

Question 10

Hydrolysis

Answer 10

Breakdown due to water