Topic 6 Muscle Contraction Flashcards

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1
Q

What is the order of the bands?
[In muscle contraction]

A

I A I
I band A band I band

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2
Q

What colour are the bands?

A

Dark-a=A bands.
Light-I=I bands.

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3
Q

What is in the middle of I bands?

A

Z line which is sarcomere

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4
Q

What is the middle of A band?

A

H Zone.

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5
Q

What filaments are present in A band?

A

In A band there is Actin and Myosin.
So thick and thin filaments together.

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6
Q

What type of filament is present in I band?

A

I band has thin filaments only so only actin.

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7
Q

What are the names of the thin and thick filaments?

A

Thin filaments are Actin.
Thick filaments are Myosin.

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8
Q

What protein in present in Actin Filament?

A

Tropomyosin

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9
Q

What binding site is in each Myosin head?

A

Each Myosin head has a binding site for Actin and binding site for ATP

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10
Q

What is the sliding filament Hypothesis?

A

Thick and thin filaments do not change length.
A bands remain constant (A bands same length)
I bands decrease
Z line move together so sarcomere gets shorter

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11
Q

What is the first thing that occurs in Sliding filament theory?

A

Action potential arrives at muscle fibre depolarising the Sacrolemma by T-Tubles causing release of Ca2+ from Sacrolemma Reticulm.

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12
Q

What do Ca2+ ions do in Muscle contraction?

A

Ca2+ bind to tropomyosin which cause to expose myosin head binding site on the actin filament

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13
Q

When Myosin head binds to the binding site on the Actin Filament what is formed?

A

Actin-Myosin cross bridge formed upon myosin and actin attachment this causes myosin to rotate to centre of Sacrolemma causing power stroke.

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14
Q

What causes Myosin head to detach and what does this do?

A

ATP is then hydrolysed by ATP hydrolase and causes myosin head to detach and reattach on further binding sites shorting sacromere causing muscle contraction.

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15
Q

When impulse stops in sliding filament theory occurs?

A

When impulse stops Ca2+ actively transported back into Sacrolemma Reticulm this allows tropomyosin to block myosin head binding sites on Actin Filament

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16
Q

Where is Slow twitch located?
Where is Fast twitch located?

A

Slow twitch located in calf muscle.
Fast twitch located in biceps.

17
Q

What is the structure of Slow Twitch and what its general properties?

A

The structure is High concentration of myoglobin- so many Mitochondria and rich blood supply.

General properties-contracts slowly and respires Aerobically for long period of time.

18
Q

What is the structure fast twitch?
What is its general properties?

A

The structure is thicker so more myosin and High storage of Glycogen.

General Properties is it contracts faster in short bursts.

19
Q

What type of filament is present in H zone?

A

In H zone there is only myosin