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NMSP - Exam 3 > Tobacco, Vape, Marijuana, CBD > Flashcards

Tobacco, Vape, Marijuana, CBD Flashcards

1
Q

What is the structure of a vape?

A

Liquid/dry material that is heated by a battery powered device into a vapor that is inhaled

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2
Q

What are the options for the liquid that can be put into vapes?

A

Flavors
Nicotine
Marijuana

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3
Q

Is vaping safe in younger adults? Why or why not?

A

NO

  • brain is still developing
  • burns possible
  • Increased risk of smoking cigs
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4
Q

Vaping is not safe in teens/young adults because their brain is still developing. What may cause damage to the developing brain?

A

Toxic metals/substances in the vape

– nicotine/marijuana etc.

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5
Q

Adolescents are more vulnerable to drug initiation/addiction because what part of their brain is not yet developed?

A

Pre-frontal cortex

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6
Q

What does the pre-frontal cortex control?

A

Executive functioning

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7
Q

With Adolescents, the pre-frontal cortex is not yet developed fully. What types of behaviors does that cause to occur usually?

A

Impulsive
Risk-taking
Possible drug initiation/vaping

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8
Q

Have lung injuries occurred with vaping even though it is safer than cigs?

A

YES

= lung illness/injury have occurred

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9
Q

What substance that was in some vapes caused serious lung illnesses/injuries?

A

Vitamin E acetate that was used to thicken THC oil

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10
Q

What is Vitamin E Acetate used for?

A

Thicken THC oil

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11
Q

When is Tobacco (nicotine) often used?

A

Major component of cigs

– Can help with smoking cessation

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12
Q

What is the fatal dose of nicotine?

A

60 mg

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13
Q

Tolerance and dependence can develop to nicotine, especially when?

A

Smoking more than 10-15 cigs per day

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14
Q

What does Nicotine impair in the brain?

A

Neuroplasticity

= ability of brain to change

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15
Q

What does Nicotine impair in the brain, and what is that?

A

Neuroplasticity

= Ability of brain to change

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16
Q

What alterations does the Neuroplasticity that occurs with Nicotine use result in?

A

Alterations in genes, cells, signaling, myelin and synaptic pruning

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17
Q

What is the mind altering component (cannabinoid) of Marijuana?

A

THC

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18
Q

Marijuana is from the Cannabis plant. Compounds that are found within it are called?

A

Cannabinoids

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19
Q

What are the symptoms of taking Marijuana?

A

Altered senses and time perception
Change in mood and body mobility
Decreased problem solving and memory

20
Q

At HIGH doses, what can Marijuana cause to occur?

A

Hallucinations
Delusions
Psychosis

21
Q

Describe the cascade of how THC is metabolized

A

THC

  • -> 11-OH-THC
  • -> 11-COOH-THC (inactive)
22
Q

What receptors and where are activated by Cannabinoids like THC?

A 
CB1 = CNS
CB2 = immune and hematopoietic cells
23
Q

How long can Marijuana be detected in the urine?

A

3-77 days (usually < 30)

24
Q

How long can Marijuana be detected in the blood/saliva and hair?

A 
Blood/Saliva = < 7 days
Hair = < 90 days
25
Q

What is a synthetic delta 9 THC?

A

Dronabinol

26
Q

What is a synthetic delta 9 THC?

A

Dronabinol

27
Q

What receptor does Dronabinol activate?

A

CB1 in the CNS

28
Q

What are the 4 general effects of Dronabinol?

A

Analgesia
Increased appetite
Muscle relaxation
Psych sx

29
Q

What psych symptoms can be seen with Dronabinol use?

A

Laughter
Increased sensation
Somatic = floating/sinking feeling

30
Q

When is Dronabinol used?

A

Anorexia in AIDs patients
Chemo-induced N/V
Obstructive sleep apnea

31
Q

When is Dronabinol used?

A

Anorexia in AIDs patients
Chemo-induced N/V
Obstructive sleep apnea

32
Q

What is a THC capsule?

A

Nabilone

33
Q

What is Nabilone?

A

THC capsul

34
Q

What is Nabilone used for?

A

Chemo-induced N/V

35
Q

What has Cannabis been efficacious at treating?

A 
Chronic (neuropathic) pain
Increasing appetite
N/V
Anxiety, PTSD
Multiple Sclerosis
36
Q

What type of pain can Cannabis treat?

A

Chronic (neuropathic) pain

37
Q

CBD stands for?

A

Cannabidiol

38
Q

What is CBD?

A

Naturally occurring (-) - CBD enantiomer

39
Q

CBD is given orally and has extensive first pass metabolism in the?

A

Liver

– 7 CYPs

40
Q

Where does CBD rapidly accumulate?

A

Adipose tissue

41
Q

What does CBD NOT produce that THC does?

A

NO Psychoactive effects

– no potential for abuse

42
Q

What differentiates CBD from THC?

A

NO psychoactive effects

NO potential for abuse

43
Q

What has CBD proven to be efficacious at treating?

A

2 rare forms of childhood EPILEPSY

– Lennox-Gastaut and Dravet Syndromes

44
Q

What is a CBD solution that can treat epilepsy?

A

Epidiolex

45
Q

What is Epidiolex?

A

CBD solution that can treat Epilepsy

– Lennox-Gastaut and Dravet Syndromes

NMSP - Exam 3 (22 decks)

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