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NMSP - Exam 3 > SNRIs > Flashcards

SNRIs Flashcards

1
Q

What are all the SNRIs?

A 
**All TCAs
Duloxetine
Venlafaxine
Desvenlafaxine
Levomilnacipran
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2
Q

What are all the SNRIs?

A 
**All TCAs
Duloxetine
Venlafaxine
Desvenlafaxine
Levomilnacipran
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3
Q

What SNRI is only for Fibromyalgia?

A

Milnacipran

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4
Q

Milnaciprain is ONLY for what condition?

A

Fibromyalgia

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5
Q

What are the 5 Tertiary Amines (TCAs)?

A 
Amitriptyline
Doxepin
Imipramine
Trimipramine
Clomipramine
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6
Q

What are the 5 Tertiary Amines (TCAs)?

A 
Amitriptyline
Doxepin
Imipramine
Trimipramine
Clomipramine
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7
Q

What are the 5 Tertiary Amines (TCAs)?

A 
Amitriptyline
Doxepin
Imipramine
Trimipramine
Clomipramine
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8
Q

What are the 4 Secondary Amines (TCAs)?

A

Nortriptyline
Protriptyline
Amoxapine
Desipramine

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9
Q

What are the 4 Secondary Amines (TCAs)?

A

Nortriptyline
Protriptyline
Amoxapine
Desipramine

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10
Q

What are the 4 Secondary Amines (TCAs)?

A

Nortriptyline
Protriptyline
Amoxapine
Desipramine

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11
Q

Which SNRI has an extra MOA and what is it?

A

Amoxapine

= Dopamine ANTAGONIST

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12
Q

What are Amoxapines MOA?

A

SNRI (secondary amine TCA)

D2 dopamine ANTAGONIST

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13
Q

Which SNRI can treat Enuresis?

A

Imipramine

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14
Q

What specific condition can Imipramine be used for?

A

Enuresis (bed wetting)

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15
Q

Which SNRI can also treat diabetic peripheral neuropathy, fibromyalgia, MSK pain and stress incontinence?

A

Duloxetine

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16
Q

TCAs can BLOCK other receptors. What are those 3 receptors?

A
  1. Histamine
  2. Muscarinic
  3. Alpha Adrenergic
17
Q

TCAs can BLOCK other receptors. What are those 3 receptors?

A
  1. Histamine
  2. Muscarinic
  3. Alpha Adrenergic
18
Q

TCAs block 3 other receptors. What are they and what side effects do they result in?

A
  1. Histamine –> CNS
  2. Muscarinic –> Anticholinergic
  3. Alpha Adrenergic –> Cardiovascular
19
Q

What are the 3 symptoms of TCA overdose?

A

Coma
Conduction abnormalities
Convulsions

20
Q

What are the 3 symptoms of TCA overdose?

A

Coma
Conduction abnormalities
Convulsions

21
Q

SNRIs have ___ sexual dysfunction than SSRIs

A

LESS

22
Q

What are 3 general side effects from SNRIs?

A

Agitation
Insomnia
HTN

23
Q

What are 3 general side effects of SNRIs?

A

Agitation
Insomnia
HTN

24
Q

If a person has a slowed heart conduction from Na+ channel blockade, what did they likely do?

A

TCA overdose

25
Q

What is the MOA for SNRIs?

A

Serotonin Norepinephrine Reuptake Inhibitors

= (-) pre-synaptic reuptake of serotonin via SERT and norepinephrine via NET

NMSP - Exam 3 (22 decks)

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