Tobacco Use And Smoking Cessation

Question 1

How many people die from tobacco use per year?

Answer 1

More than 8 million!
(Half its users)

Question 2

What 8s the MPOWER package of 6?

Answer 2

Policies to stop smoking

Monitor
Protect
Offer
Warn
Enforce
Raise

Question 3

Diagnostic criteria for smokers

Answer 3

1. DSM 5
2. RACGP = NICOTINE DEPENDANCE
   Q. How soon after waking do you have your first cig?
   Q. How many cigarettes a day?
   Q. Cravings?

Question 4

Indicators or nicotine dependence?

Answer 4

1. SMOKING WITHIN 30 MINS OF WAKING (most reliable indicator)
2. More than 10 cigarettes per day

Question 5

Stages of quitting

Answer 5

1. Precontemplation
2. Contemplation
3. Preparation
4. Action
5. Maintenance

Question 6

Lapse Vs Relapse?

Answer 6

Lapse = slip up with a quick return to maintenance

Relapse = full blown return to smoking

Question 7

Effects of smoking on these drugs

Caffeine
Clozapine
Erlotinib
Irinotecan
Theophylline

Answer 7

Caffeine = smoking increases clearance
(When stopping smoking, decrease caffeine by half)

Clozapine = smoking increases clearance

(All the same)

Erlotinib
Irinotecan
Theophylline

Question 8

Varenicline
MOA

Answer 8

Partial agonist at subtype of neuronal nicotinic acetylcholine receptors

Reduces symptoms of nicotine withdrawal

Question 9

Vareniciline

Most common side effect?

Answer 9

Nausea
30% of patients

If intolerable, reduce the dose or take with food

Question 10

When should Bupropion be taken during the day?

Answer 10

In the morning for the first few days
To avoid sleep disturbance