Depression

Question 1

name SSRIs (6)

Answer 1

Citalopram
Escitalopram
Fluoxetine
Fluvoxamine
Paroxetine
Sertraline

Question 2

Name SNRIs
3

Answer 2

Desvenlafaxine
Duloxetine
Venlafaxine

Question 3

Name
TCAs

Answer 3

Amitriptyline
Clomipramine
Dosilepin
Imipramine
Nortriptyline

Question 4

Name MOAi
2

Answer 4

Phenelzine
Trantlcypromine

Question 5

Which SSRI make you drowsy
(Don’t give you insomnia)
2

Answer 5

Fluvoxamine
Paroxetine

Question 6

Opioids that can contribute to SEROTONIN TOXICITY
4

Answer 6

Dextromethorphan
Fentanyl
Pethidine
Tramadol

Question 7

DDI of SSRI = CYP INTERACTIONS

1. …1A4 inhibitor=
2. …2D6 inhibitor=
3. …3A4 inhbitior=

Answer 7

1. …1A4 inhibitor= Fluvoxamine
2. …2D6 inhibitor= clomipramine, Fluvoxatine, Paroxetine
3. …3A4 inhbitior= Fluvoxamine

Question 8

Moa of
Tricyclic antidepressants

Answer 8

Block reuptake of 5HT and NAd into presynaptic terminal

Question 9

Other antidepressants

Miratazapine MOA
and
Reboxetine MOA

Answer 9

Miratazapine = post synaptic blockage of 5HT2/3 receptors

Reboxetine = NRI (and weak SRI)

Question 10

Agomelatine

Considered when all else fails:
moa

Answer 10

Melatonin Receptor agonist (MT1 and MT2) and 5HT2c receptor antagonists

Question 11

Vortioxetine (brintellix)

MOA as a antidepressant and anxioloytic

Answer 11

Inhibits reuptake of 5HT and Antagonist of 5HT3 and agnoisr of 5HT1A

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