Epilepsy Flashcards
1
Q
Major drug classes of antiepletics
A
1 Modulation of voltage gated ion channel
2 enhancement of GABA mediated inhibitory neurotransmission
3 attenuation of glutamate mediated excitatory neurotransmission
2
Q
Name CALCIUM channel blockers
A
Gabapentin
Ethosuximide
Zonisamide
Levetiracetam
3
Q
Na channel gate Inhibitors
A
Phenytoin
Carbamezepine
Oxcarbazepine
Lamotrigine
Lacosamide
Zonisamide
4
Q
Ganaxolone
moa
New treatment
A
GABA-A Receptor Modulator
5
Q
Which drug is contraindicated for use in DRAVET SYNDROME
what to use instead?
A
AVOID CARBAMEZEPINE
INSTEAD use clobazem and stiripentol
6
Q
Which gene mutations is common with Dravet Syndrome
A
SCN1A gene mutations
(Na channel)
7
Q
Which receptors does CBD work on
A
5HT3
alpha 7 nicotinic acetylcholine receptors
