Illicit Drugs Flashcards

1
Q

Cannabis

MOA

A

THC increases DA release in nucleus accumbens

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2
Q

Cocaine

MOA

A

Blocks MONOAMINE uptake

Increases synaptic DA, NA, 5HT levels

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3
Q

LSD

MOA

A

Binds to 5HT1, 5HT2A, 5HT2C, DA, Adrenergic receptors

5H2A = hallucinations

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4
Q

MDMA ecstacy

MOA

A

Elevates brain 5HT levels

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5
Q

Caffeine

MOA

A

Adenosine A1 and 2A Antagonist

RELEASES DA, 5HT, Ach, Glutamate, GABA

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6
Q

Alcohol

MOA

A

Enhances GABA mediated neurotransmitters

(Like benzos)

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7
Q

What is ANTABUSE? (DISULFIRAM)?

A

Treatment for chronic alcoholism

Inhibits acetdehyde deydrogenase

= accumulation of acetaldehyde

=alcohol flush reaction

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8
Q

Why do ppl feel CLOSENESS when taking MDMA (ecstacy)?

A

MDMA causes significant increases in the oxytocin.

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