Illicit Drugs Flashcards
1
Q
Cannabis
MOA
A
THC increases DA release in nucleus accumbens
2
Q
Cocaine
MOA
A
Blocks MONOAMINE uptake
Increases synaptic DA, NA, 5HT levels
3
Q
LSD
MOA
A
Binds to 5HT1, 5HT2A, 5HT2C, DA, Adrenergic receptors
5H2A = hallucinations
4
Q
MDMA ecstacy
MOA
A
Elevates brain 5HT levels
5
Q
Caffeine
MOA
A
Adenosine A1 and 2A Antagonist
RELEASES DA, 5HT, Ach, Glutamate, GABA
6
Q
Alcohol
MOA
A
Enhances GABA mediated neurotransmitters
(Like benzos)
7
Q
What is ANTABUSE? (DISULFIRAM)?
A
Treatment for chronic alcoholism
Inhibits acetdehyde deydrogenase
= accumulation of acetaldehyde
=alcohol flush reaction
8
Q
Why do ppl feel CLOSENESS when taking MDMA (ecstacy)?
A
MDMA causes significant increases in the oxytocin.