Thyroid drugs Flashcards

1
Q

early sign of agranulocytosis

A

sore throat

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2
Q

what might carbimazole cause

A

agranulocytosis > neutropenia > sepsis

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3
Q

drug used in first trimester of pregnancy in hyperthyroidism

A

Propylthiouracil- PTU

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4
Q

dosage for ptu

A

twice daily

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5
Q

dosage for carbimazole

A

once daily

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6
Q

dosage for levothyroxin e

A

once daily before breakfast

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7
Q

first line drug in hyper

A

carbimazole

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8
Q

MOA of carbimazole

A

blocks TPO so block thyroid hormone synthesis so decreases production of t3/t4

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9
Q

does carbimazole affect the foetus

A

yes

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10
Q

first line drug in hypo

A

levothyroxine

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11
Q

when might dosage of levothyroxine increase

A

in pregnancy

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12
Q

when might you face adverse effects of levothyroxine

A

when the dosage is too high - signs of hyperthyroidism

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13
Q

what may affect the absorption of levothyroxine

A

iron tablets, calcium tablets, PPI’s

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14
Q
A
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