Nephropathy Flashcards

1
Q

what is diabetic nephropathy

A

A progressive kidney disease caused by damage to the capillaries in the kidneys’ glomeruli

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2
Q

what is diabetic nephropahty charcaterised by

A

proteinuria and diffuse scarring in the glomeruli

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3
Q

how is it diagnosed

A

elevated urine protein and or reduced renal function

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4
Q

what should patients with microalbuminaemia be strated on regardless of hba1c

A

SGLT2 inhibitor

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5
Q

what can prevent further decline

A

ace inhibitor, sglt2i, bp monitoring

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6
Q

complications of nephropathy

A

hypertension
decline in renal function
- gfr will drop 1 ml/min / month if untreated

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7
Q

what test identifies kidney disease

A

ACR test

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8
Q

what is albumin

A

a protein

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9
Q

what is creatine

A

waste product from muscle metabolism

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10
Q

why is albumin and creatine measured

A

albumin signifies kidney damage as healthy ones prevent significant amounts of protein leaking into the urine

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11
Q

proteinuria values

A

acr > 30, pcr >50

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12
Q

does proteinuria show up on dip stick

A

yes

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13
Q

does microalbuminemia show up on dip stick

A

no

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14
Q

microalbuminaemia values

A

acr <30, pcr <50

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15
Q

how to prevent nephropathy

A

good glycaemic control

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16
Q

effect of ACEI/ARB in nephropathy

A

dilates renal arterioles so less pressure
decrease protenuria
decrease gfr

17
Q

established microalb

A

if 2/3 tests positive

18
Q

what might cause false positives

A

menstruation
vaginal discharge
uti
PREGNANCY
non diabetic renal disease

19
Q

first line treatment

A

ACE/ARB

20
Q

GFR

A

measures filter through glomeruli a minute
about 120 mils a minute = normal

21
Q

what happens to gfr as renal function declines

A

gfr reduces

22
Q

similiarity of SGLT2I and ACEI

A

reduce filtration pressure by decreasing renal afferent dilatation

23
Q
A