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1
Q

diagnosis of addisons

A

shory synacthen test

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2
Q

most ocmmon side effect of gliclazide

A

weight gain

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3
Q

recommended monitoring glucose in tpe 1

A

at least 4 times a day

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4
Q

first line investigation in suspected primary hyperaldosteronism

A

plasma renin/ aldosterone ratio

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5
Q

obesity classes

A

25-29 overweight
30-35- class 1
35-40- class 2
40>- class 3

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6
Q

definitive management of primary hyperparathyroidism

A

total thyroidectomy

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7
Q

painful diabetic neuropathy management

A

duloxetine

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8
Q

what should be used in new cass of graves to control symptoms

A

propanolol

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9
Q

c peptide levels in diabetes

A

low in type 1
high/ normal n type 2

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10
Q

what anti diabetic drugs are linked to necrotising fascittis of the genittials

A

sglt2 inhiitprs

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11
Q

most common cause of cushings syndrome

A

pituitary adenoma

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12
Q

what causes hyperpigmentation- addisons or cushings

A

addisons

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13
Q

first line test for acromegaly

A

serum igf-1

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14
Q

big hands

A

acromegaly

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15
Q

time difference between hhs and dka

A

hhs comes on in days and dka comes on within hours

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16
Q

what to switch triple therapy for in type 2 if not improving

A

glp-1 mimetic

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17
Q

hba1c in prediabetes

A

42-47

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18
Q

hba1c diagnostic of diabetes

A

48 or above

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19
Q

drugs which can cause weight gain

A

zides- sulfonylureas

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20
Q

what are utis a side effect of

A

sglt2 inhibitors

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21
Q

uncommon yet specific feature of graves

A

pretibial myxoedeoma

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22
Q

what to give in hypoglycaemia with impaired gcs

A

iv glucose

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23
Q

what should patients wirth addisons be given in case of an adrenal crisis

A

hydrocortison IM

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24
Q

electrolyte abnormality in cushings

A

hypokalaemic metabolic alkalosis

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25
how does cushings cause its electrolyte abnormality
due to increased excretion of potassium and hydrogen ions
26
abnormal blood test causing gynaecomastia
prolactin
27
most modifiable risk factor in development of thyroid eye disease
smoking
28
correct rate of insulin to prescribe in dka
0.1/kg/hr
29
drug to reduce cerebral oedema
dexamethasone
30
what is de quervains thyroiditis assoc with
raised esr and tender goitre
31
complication of fluid resus in dka
cerebral oedema
32
suscpsion of cerebral oedema test
ct
33
lipid rich core
benign adenoma
34
target hba1c with sulfonylureas
53
35
what type of drug is sitagliptin
ddp 4 inhibitor
36
primary hyperaldosteronism features
hypokalaemia and hypertension
37
drug causing thrush
sglt2
38
addisonian crisis blood results
low sodium high potassium low glucose
39
what does parathyroid hromone cause
excretion of phosphate
40
thiazides and calcium correlation
causes hypercalcaemia
41
what does kinefelters syndrome cause
high lh and low testosterone
42
what does over replacement of levothyroxine enhance
risk of osteoporosis
43
diagnostic for cushings syndrome
t low dose dexamethasone
44
what should happen to regular insulin rwgime in dka
continue long acting stop short acitng
45
management of addisons
hydrocortisone and fludrocortison
46
exogenous insulin overdose signs
low c peptide high insulin in serum
47
hypogylcaemia treatment if patient is conscious and able to speak
glucogel orally
48
purpose of high dose dexamethasone
to loaclise source of excess cortisol
49
how to treat pituitary adenoma
transphenoidal surgery
50
treatment for toxic nodule
radio active iodine
51
hyperthyroidism treatment for first trimester of preg
PTU
52
causes of raised prolactin
the p's pregnancy prolactinoma physiological polycystic ovarian syndrome primary hypothyroidism phenothiazines, metoclopramide, domperidone
53
managemtn of primary hyperaldosteronism
spironolactone
54
what is assoc with carbimazole use
agranulocytosis
55
initial management of graves
propanolol
56
diagnosis of diabetes
fasting glucose 7 random 11.1 or above if asymptomatic then needs done twice
57
anti diabetic drug causing hypoglycaemia
sulfonylureas
58
is fludrocortisone requored for addisonian crisis
no
59
hypercalcaemia on ecg
shortened qr interval as it speeds up repolarisation
60
management of hypercalcaemia
fluids , bisphosphonates
61
pneumonic for primary hyperpara
moans groans bones for hypercalcaemia
62
another word for addisons
primary hyperaldosteronism
63
what drug may result in gynaecomastia
GNRH agonists- goseriln
64
what antidiabetic causes hypogylcaemia
sulfonylureas
65
hypocalacaemia on ecg
prolonged qt interval
66
most common cause of primary hypoaldosteronism
bilateral idiopathic adrenal hyperplasia
67
bisoprolol or propanolol in graves
propanolol
68
hyperaldosteronism with bilateral adrenal disease managemrnt
potassium sparing diuretic - amiloride
69
pseudohypopararthyroidism
low calcium high phosphate now renal disease raised pth
70
elevated metanephrines
phaeocromocytoma
71
treatment for phaeochromocytoma
phenoxybenzamine
72
what is conns syndrome caused by
aldosterone producing adrenal adenoma
73
conns syndrome features
muscle weakness, fatigue, headaches
74
painful smooth goitre
de quervains thyroiditis
75
pepperpot skull
primary hyperparathyroidism
76
primary hyperaldosteronism characteristics
fatigue, muscle weakness, headache, hypokalaemia, hypertension
77
what is low in hypercalcaemia secondary to malignancy
pth
78
sick euthyroid syndrome
low t3/t4 with normal tsh in an acutely unwell patient
79
commonest cause of annovulation in females
pcos
80
MOA of carbimazole
inhibits TPO enzymes
81
first line cushings
metyrapone
82
what does an epithelial maligancny mean
that the diagnosis is carcinoma
83
acropachy assoc
graves
84
SIADH results
high urinary sodium and high urinary osmolality
85
what is pioglitazone contra in
heart faikure
86
what is klinefelter assoc with
above average heigh and difficulty to conceive
87

Endocrine (48 decks)

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