Thrombosis Drug usage and side effects

Question 1

Unfractionated heparin

Answer 1

Use: Prevention and treatment of venous thromboembolism

SE: HIT and bleeding

Question 2

Dalteparin

Answer 2

Use: Prevent thrombosis and embolism from clots

SE: Bleeding

Question 3

Enoxaparin

Answer 3

Use: Drug of choice in pregnancy; prevention and treatment of venous thromboembolism

SE: HIT; bleeding; osteoporosis and thrombocytopenia uncommon

Question 4

Tinzaparin

Answer 4

SE: HIT; Osteoporosis and thrombocytopenia uncommon

Question 5

Fondaparinux

Answer 5

Use: Given for HIT

SE: Bleeding and NO ANTIDOTE

Question 6

Warfarin

Answer 6

Use: Long term antigoagulation

SE: Warfarin skin necrosis
bleeding

Question 7

Bivalirudin

Answer 7

Use: Percutaneous coronary intervention

SE: bleeding

Question 8

Argatroban

Answer 8

Use: Percutaneous coronary intervention

SE: bleeding

Question 9

Dabigatran

Answer 9

Use: DVT / PE; Afib

SE: Bleeding

Question 10

Rivaroxaban

Answer 10

Use: DVT/PE prophylaxis

SE: Bleeding

Question 11

Apixaban

Answer 11

Use: DVT/PE prophylaxis

SE: Bleeding

Question 12

Alteplase

Answer 12

Use: Acute MI, acute Stroke, central DVT, multiple PE

Question 13

Reteplase

Answer 13

Use: Acute MI, acute Stroke, central DVT, multiple PE

Question 14

Tenecteplase

Answer 14

Use: Acute MI, acute Stroke, central DVT, multiple PE

Question 15

Aspirin

Answer 15

Use: Often as baby aspirin to prevent and treat MI and stroke

Question 16

Dipyridamole

Answer 16

Use: Weak anti-platelet effect

Question 17

Clopidogrel

Answer 17

Use: Precent and treat ACS, stroke, peripheral vascular disease, angina, stent

SE: Bleeding and TTP rare

Question 18

Abciximab

Answer 18

SE: may illicit immune response

Question 19

Eptifibatide

Answer 19

SE: Bleeding; ACS; PCI

Question 20

Tirofiban

Answer 20

SE: Bleeding; NSTE ACS