Cholinergic Receptor Inhibitors Therapeutics

Question 1

Atropine

Answer 1

mydriasis; cycloplegia

Question 2

Scopolamine (transderm-scop)

Answer 2

prevent or reduce motion sickness

Question 3

Dicyclomine (Bentyl)

Answer 3

Reduce transient hypermotility

Question 4

Tropicamide (Mydriacyl)

Answer 4

Mydriasis; cycloplegia

very rapidly metabolized

Question 5

Tolterodine (Detrol)

Answer 5

Treat transient cystitis; postoperative bladderspasms; incontinence

Question 6

Benztropine (Congentin)

Answer 6

Treat manifestations of parkinson’s disease

crosses BBB

Question 7

Ipratropium (Atrovent)

Answer 7

Bronchodilation in asthma or COPD

Question 8

Tiotropium (spiriva)

Answer 8

Bronchodilation in asthma or COPD

Question 9

Hexamethonium (Methium)

Answer 9

Hypertensive crisis; “Bloodless” field surgery

Question 10

Mecamylamine

Answer 10

Hypertensive crisis; “Bloodless” field surgery

Question 11

Succinylcholine (Anectine)

Answer 11

Brief procedures ( eg. tracheal intubation, reset dislocated joints) produces flaccid paralysis within a minute, only lasts for a few minutes

Question 12

Tubocurarine (Curare)

Answer 12

Muscle Relaxant for surgery w/o deep anestheisa

lasts 30-60 min

Question 13

Mivacurium (Mivacron)

Answer 13

Muscle Relaxant for surgery w/o deep anesthesia

rapidly hydrolyzed short acting

Question 14

Botulinum Toxin A (Botox)

Answer 14

Reduce frown lines and wrinkles; achalasia; strabismus; oromandibular dystonia

Question 15

What are the side effects of the muscarinic receptor blockers?

Answer 15

general block of muscarinic functions

Question 16

What are the side effects of the N1 blockers?

Answer 16

Respiratory paralysis; disturbance of autonomic function.