Adrenergic Drugs Class/mechanism Flashcards

1
Q

Norepinephrine (levophed)

A

Nonselective agonist
Alpha 1 and 2
Beta 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Epinephrine

A

nonselective agonist
alpha 1
Beta 1 and 2
(Alpha 2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Amphetamine

A

indirect acting agonist

Increases release of NE and blocks reuptake.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Isoproterenol (Isuprel)

A

Non-selective Beta agonist

Beta 1 and 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Dobutamine

A

Selective agonist

Beta 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Albuterol (Proventil)

A

Selective agonist

Beta 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Terbutaline (Brethine)

A

Selective agonist

Beta 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Phenylephrine (Neosynephrine)

A

Selective agonist

Alpha 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Clonidine (Catapres)

A

Selective agonist

CNS Alpha 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

alpha-methyldopa (Aldomet)

A

Selective agonist

Metabolite (a-methylnorepinephrine) activates CNS alpha 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Fenoldopam (Corlopam)

A

Selective dopamine agonist

D1 only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dopamine

A

mixed acting (Direct and indirect) agonist
D1
alpha 1
Beta 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Phentolamine (Regitine)

A

Non-selective alpha antagonist

alpha 1 and 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Phenoxybenxamine (Dibenzyline)

A

Non-selective alpha antagonis
Alpha 1 and 2
non competitive covalent bond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Prazosin (minipress)

A

selective antagonist

alpha 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Terazosin (hytrin)

A

selective antagonist

alpha 1

17
Q

Propanolol (inderal)

A

Nonselective beta antagonist (1st gen)

Beta 1 and 2

18
Q

Timolol (Betimol)

A

nonselective beta antagonist (1st gen)

Beta 1 and 2

19
Q

Metropolol (Lopressor)

A

Selective Beta antagonist (2nd gen)

Beta 1

20
Q

Atenolol (Tenormin)

A

Selective beta antagonist (2nd Gen)

Beta 1

21
Q

Bisoprolol (Zebeta)

A

Selective beta antagonist (2nd Gen)

Beta 1

22
Q

Carvedilol (Coreg)

A

Nonselective Beta antagonist (3rd Gen A)
Beta 1 and 2
plus alpha 1

23
Q

Labetalol (Trandate)

A

Nonselective beta antagonist (3rd gen A)
Beta 1 and 2
plus alpha 1

24
Q

Betaxolol (Kerlone)

A

Selective beta antagonist (3rd gen B)
Beta 1
Plus ca2+ channel blocking

25
Q

Tyramine

A

indirect acting agonist

increases CYTOPLASMIC NE reslease

26
Q

Cocaine

A

Prevent NE reuptake

27
Q

Guanethidine (Ismelin)

A
Nerve ending blocker
False neurotransmitter (Vesicles become full of guanethidine rather than NE)
28
Q

Reserpine

A

Nerve ending blocker

Release of empty vesicles (NE is not taken into vesicles b/c it binds uptake transporter and stops it)

29
Q

Alpha-methyltyrosine (Metirosine)

A

Nerve ending blocker

Inhibit tyrosine hydroxylase (Decreases NE synthesis)

30
Q

Ephedrine (Pretz-D)

A

Mixed direct beta 2 and indirect agonist