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Pharm Unit 2 MJC > Arthritis and Gout Drugs Use and Side effects > Flashcards

Arthritis and Gout Drugs Use and Side effects Flashcards

1
Q

Indomethacin

A

Use: rheumatoid arthritis; acute gouty arthritis

SE: gastric and duodenal ulcers

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2
Q

Naproxen

A

Use: Rheumatoid arthritis and acute gouty arthritis

SE: Gastric and duodenal ulcers

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3
Q

COX-2 inhibitors

A

Use: Superseding conventional NSAIDS for rheumatoid arthritis

SE: 50% fewer gastric and duodenal ulcers

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4
Q

Quinolones

A

Use: Rheumatoid arthritis, SLE

SE: Retinal damage

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5
Q

Glucocorticoids

A

Use: Rheumatoid arthritis; acute gouty arthritis (intraarticular injection for relief of acute monoarticular gout)

SE: Cushing symptoms

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6
Q

Sulfasalazine

A

Use: Rheumatoid arthritis

SE: N/V, skin rashes, neutropenia (30% of patients discontinue) headaches

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7
Q

Methotrexate

A

Use: Rheumatoid arthritis

SE: Nausea, stomatitis, hepatotoxicity (rare)

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8
Q

Leflunomide

A

Use: Rheumatoid arthritis

SE: Diarrhea, hepatotoxicity

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9
Q

Etanercept

A

Use: Rheumatoid arthritis

SE: none

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10
Q

Infliximab

A

Use: Rheumatoid arthritis

SE: Antigenic response to mouse Ab

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11
Q

Adalimumab

A

Use: Rheumatoid arthritis

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12
Q

Golimumab

A

Use: Rheumatoid arthritis

SE: Risk of infections

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13
Q

Certolizumab

A

Use: Rheumatoid arthritis

SE: Risk of infections

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14
Q

Anakinra

A

Use: Rheumatoid arthritis

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15
Q

Tocilizumab

A

Use: Rheumatoid arthritis

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16
Q

Rituximab

A

Use: Rheumatoid arthritis

SE: Infections; hypersensitivity reactions

17
Q

Abatacept

A

Use: Rheumatoid arthritis

SE: Headaches and infections

18
Q

Colchicine

A

Use: Acute gouty arthritis

SE: Low therapeutic index, long term use causes peripheral neuropathy and neutropenia. Nausea vomiting and toublesome diarrhea

19
Q

Probenecid

A

Use: Chronic tophaceous gout

SE: Urate crystal mobilization and acute gouty arthritis and GI irritation

20
Q

Allopurinol

A

Use: Chronic tophaceous gout

SE: Acute attacks of gouty arthritis early in treatment due to mobilization of crystals

21
Q

Febuxostate

A

Use: Chronic Tophaceous gout

SE: Nausea, rash, arthralgias

22
Q

Pegolitcase

A

Use: Chonic tophaceous gout

Pharm Unit 2 MJC (25 decks)

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