THERAPEUTICS - codeine Flashcards
what type of drug is codeine?
opiate
how do opiates act?
centrally acting - morphine agonists and opioid receptors
what is morphine?
an analgesic
what does morphine treat?
acute severe pain - continuous dull
what are the effects of morphine?
drowsiness
sedation
euphoria
cough suppression (antitussive)
what are the unwanted effects of morphine?
nausea and vomiting (initial)
urticaria/ pruritis
resp depression
constipation
confusion
what are the doses for morphine it’s different forms?
PO 10-30mg
IV 2.5-15mg/ 70kg
SC 5-20mg/ 70kg
100mg 24hrs
what are the contraindications and special considerations for morphine?
dependence
UC
suspected head injury
acute alcoholism
reduced resp
hepatic and renal insufficiency
hypersensitivity
what is codeines chemical name?
dihydrocodeine
what is codeine?
naturally occurring oral opioid
what is codeine used for?
mild to moderate pain
in combination with paracetamol (cocodamol, codydramol)
where is codeine metabolised?
liver
what is codeines half life?
3 hours
what are the contraindications of codeine
nausea
hypotension
urticaria/ pruritis
what is the standard adult dose of codeine?
30-60mg 4-6 hourly
max 240mg in 24 hours
