The Immune Reaction Flashcards
The first phagocytic WBC to encounter antigen
Neutrophil
The second WBC, circulating in BS, will map the antigen
Lymphocyte
The antibody producing lymphocyte cells within the lymph node are called
Plasma cells
What antibodies do
Neutralize antigen (prevents from binding to other cells) Opsonization- holds antigen for phagocyte to engulf Activated other defense systems
Opsonization
Antibodies binding and holding antigen (making easier for phagocyte to engulf)
Replicas of antibody producing cells that remain in lymph nodes
Memory cells
Reactions that occur in blood vessels/ tissue in response to injury/ stimulation by physical, chemical, or biological agent
Inflammation
Characteristics of inflammation
Redness, heat, swelling, pain
Define vasodilation
Dilation of blood vessels
What causes vasodilation that accompanies inflammation
Caused by substances released by damaged tissue cells and cellular debri
Why vasodilation and inflammation occur (in theory)
Natural defense, brings white blood cells and antibodies to site
What causes the swelling that accompanies inflammation
Vasodilation causes fluid to leak out of blood vessel
The booster response is also called
The anamnestic response
Why booster vaccine shots are given
AB production takes time to occur, with each exposure AB production is faster and in greater quantities
Ab how long does is take (after first exposure) to produce a sufficient amount of antibodies
2 weeks
List the sequence of an immune reaction
Antigen enters
Phagocytic neutrophil (wbc) tries to destroy
Lymphocytes circulating in blood stream recognizes, binds, and maps
Binds to lymphocytes(plasma cells) within lymph nodes
Abs produced by plasma cells
How a lymphocyte maps an antigen
Activated ribosomes, “remembers” receptors on pathogen
An antibody binding to an antigen can trigger
Inflammation
Examples of tests that measure immune response
Agglulation tests, enzyme linked immunosorbant assay (ELISA), Fluorescent Ab Test (FA), radioactive antibody Test (RIA)
