The Action Potential Flashcards

1
Q

What is the characteristic profile of action potentials

A

Properties of voltage gated Na and K channels

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2
Q

how to neurons use electrical signals?

A

In the forms of action potentials to communicate with each other

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3
Q

How is the communication between neurons done

A

By propagation of an electrical signal and release of neurotransmitters

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4
Q

At rest, the cell membrane is much more permeable to which ion?

A

K+

- is the main ion the contributes to the RMP value

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5
Q

At rest, which ion is the cell membrane slightly permeable to?

A

Na+

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6
Q

What controls permeability of a neuron

A

gated channels

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7
Q

What do mechanically gated ion channels do

A

Open in response to mechanical stimulation

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8
Q

What do chemically gated ion channel do

A

Open in response to a chemical binding

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9
Q

What do voltage-gated channels do

A

Open in response to a voltage change

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10
Q

Difference between Na+ and K+ voltage gated channels

A

Na+ is faster to open where as K+ channel is lazy and slow to close

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11
Q

What is depolariztiton

A

Cell becomes more positive

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12
Q

What is repolarization

A

The depolarized membrane returns to RMP

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13
Q

What is the threshold

A

The minimum depolarization that will initiate an action potential
-55mV

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14
Q

What is hyperpolarization

A

Cell becomes more negative

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15
Q

Where to graded potentials occur

A

neuron dentrites

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16
Q

How do graded potential occur

A

Either depolarization or hyper polarization caused by opening voltage gated channels

17
Q

What is a graded potential proportional to

A

Amplitude of potential is directly proportional to the stimulus strength

18
Q

What are the 2 reasons why graded potentials can only travel a short distance and lose strength over time

A
  1. Current leak

2. Cytoplasmic resistance

19
Q

In what part of the neuron does the stimulus have to reach in order to generate an action potential

A

axon hillock with at least -55mV

20
Q

What are the 3 important things about action potentials

A
  1. All or none
  2. Unidirectional
  3. Always same amplitude and duration
21
Q

What is the absolute refractory period

A

When a a depolarized cell is returning back to the RMP, no action potentials can be generated until the channels are back to their resting position

22
Q

Which gate is responsible for the absolute refractory period

A

Inactivation gate

23
Q

What is the loss of K+ through the potassium channel responsible for?

A

hyper polarization of the cell

-action potentials can be generated here but has to be a strong enough stimulus to push it over the threshold