Test 6 - pharm

Question 1

Furosemide class, mechanism of action, and uses

Answer 1

Diuretic

inhibits NKCC2 pump

edema, hypercalcemia, hypertension

Question 2

Furosemide SAE

Answer 2

hypokalemia, ototoxicity

Question 3

Hydrochlorothiazide class, mechanism of action, and uses

Answer 3

Diuretic

inhibits NCC pump

congestive heart failure, hypercalciuria, hypertension

Question 4

Hydrochlorothiazide SAE

Answer 4

hypokalemic metabolic alkalosis

Question 5

Amiloride class, mechanism of action, and uses

Answer 5

diuretic

inhibits ENaC Na+ channel

congestive heart failure, hypertension, hypokalemia

Question 6

Amiloride SAE

Answer 6

hyperkalemia

Question 7

Spironolactone class, mechanism of action, and uses

Answer 7

diuretic

aldosterone receptor antagonist

congestive heart failure, hyperaldosteronism, hypertension

Question 8

Spironolactone SAE

Answer 8

hyperkalemia, endocrine effects

Question 9

Tolvaptan class, mechanism of action, and uses

Answer 9

Diuretic

V2 vasopressin receptor antagonist

SIADH, hyponatremia

Question 10

Tolvaptan SAE

Answer 10

nephrogenic diabetes insipidus, hepatotoxicity

Question 11

Lisinopril class, mechanism of action, and uses

Answer 11

RAAS inhibtor

angiotensin converting enzyme inhibitor

congestive heart failure, hypertension, diabetic renal disease

Question 12

Lisinopril SAE

Answer 12

bradykinin cough reflex, hyperkalemia, teratogenic

Question 13

Valsartan class, mechanism of action, and uses

Answer 13

RAAS inhibitor

angiotensin-II receptor antagonist

congestive heart failure, hypertension

Question 14

Valsartan SAE

Answer 14

hyperkalemia, teratogenic

Question 15

Metoprolol class, mechanism of action, and uses

Answer 15

adrenergic

β1-adrenergic receptor antagonist

congestive heart failure, hypertension

Question 16

Metoprolol SAE

Answer 16

bradycardia, AV block, CNS sedation

Question 17

Labetalol class, mechanism of action, and uses

Answer 17

adrenergic

mixed α1- and β1-adrenergic receptor antagonist

pregnancy-induced hypertension, hypertensive crisis

Question 18

Labetalol SAE

Answer 18

bradycardia, AV block, CNS sedation

Question 19

Doxazosin class, mechanism of action, and uses

Answer 19

adrenergic

α1-adrenergic receptor antagonist

benign prostatic hypertrophy, hypertension

Question 20

Doxazosin SAE

Answer 20

orthostatic hypotension, reflex tachycardia

Question 21

Clonidine class, mechanism of action, and uses

Answer 21

adrenergic

α2-adrenergic receptor agonist

ADHD, hypertension

Question 22

Clonidine SAE

Answer 22

severe withdrawal, sedation

Question 23

Verapamil class, mechanism of action, and uses

Answer 23

Ca2+ channel blocker

cardioselective L-type Ca2+ channel blocker

angina, arrhythmias, hypertension

Question 24

Verapamil SAE

Answer 24

excessive cardiac depression, constipation

Question 25

Amlodipine class, mechanism of action, and uses

Answer 25

Ca2+ channel blocker

vascular selective L-type Ca2+ channel blocker

angina, arrhythmias, hypertension

Question 26

Amlodipine SAE

Answer 26

hypotension, flushing, dizziness

Question 27

Ambrisentan class, mechanism of action, and uses

Answer 27

?

Endothelin-A receptor antagonist

pulmonary hypertension

Question 28

Ambrisentan SAE

Answer 28

hepatic impairment, headache

Question 29

Hydralazine class, mechanism of action, and uses

Answer 29

?

vascular smooth muscle K+ channel activator

hypertensive crisis, pregnancy induced hypertension, heart failure

Question 30

Hydralazine SAE

Answer 30

tachycardia, salt and water retention

Question 31

Sildenafil class, mechanism of action, and uses

Answer 31

?

Phosphodiesterase 5 inhibitor

pulmonary hypertension, angina, erectile dysfunction

Question 32

Sildenafil SAE

Answer 32

tachycardia, hypotension, vision disturbances

Question 33

Epoprostenol class, mechanism of action, and uses

Answer 33

?

Prostacyclin I2 analogue

pulmonary hypertension, Raynaud’s syndrome

Question 34

Epoprostenol SAE

Answer 34

hypotension, flushing, dizziness