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DDS > Tablet > Flashcards

Tablet Flashcards

1
Q

Solid dosage form that contain active ingredients & excipients prepared by either molding or compression

A

Tablets

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2
Q

Most common
Most Stable
Most tamper-proof
Dosage form

A

Tablet

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3
Q

Advantages of Tablets

A

Precision and Low control variability
Low Manufacturing cost
Easy to package and ship
Appropriate for special release form
Simple to identify
Essentially tamper-proof

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4
Q

Disadvantages of Tablets

A

Good compatiblity is required
Resist compression
Requires encapsulation before compression

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5
Q

Tablet Types and Classes

A

Tablets for oral ingestion
Tablets used in oral cavity
Tablets used to prepare solution

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6
Q

Tablets formed by compression and in simplest form, contain no special coating

A

Conventional Compressed Tablets

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7
Q

Compressing additional tablet granulation on previosuly compressed granulation

A

Multiple Compressed Tablets - Layered Tablet

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8
Q

Compressing another granulation layer/outer shell around the preformed tablet

A

Multiple Compressed Tablets: Layered Tablet

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9
Q

Compressing another granulation layer/outer shell around the preformed tablet

A

Multiple Compressed Tablets: Press coated Tablet/Dry coated tablet or Compression Coated

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10
Q

Use of Multiple Compressed Tablets

A

Separate incompatible ingredients
Produce prolonged or repeated release profiles

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11
Q

Use of Multiple Compressed Tablets

A

Separate incompatible ingredients
Produce prolonged or repeated release profiles

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12
Q

Compressed talets coated by sugar solution

A

Sugar Coated Tablet

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13
Q

Sugar Coated Tablet

A

Most elegant solid dosage form
Most difficult and time consuming to produce
50 -100% increase in size and weight

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14
Q

Use of Sugar Coated Tablet

A

To improve appearance
Mask unpleasant taste or smell
Protect from Oxidation

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15
Q

Compressed tablets coated w/ a thin layer of a insoluble or soluble polymer

2 - 3% increase in weight

A

Film Coated Tablets

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16
Q

Use of Film Coated Tablets

A

Protect drug from atmospheric conditions

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17
Q

Compressed tablets coated with substances that resist solution in gastric fluid but disintegrate in intestine

Delayed Action tablet

A

Enteric Coated Tablets

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18
Q

Use of Enteric Coated Tablet

A

To protect the drug which are inactivated destroyed in stomach

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19
Q

Enteric coating

A

Shellac
Cellulose Acetate Pthalate (CAP)

20
Q

Intended to be chewed and swallowed

A

Chewable Tablets

21
Q

Diluent used in Chewable Tablets

A

Mannitol

22
Q

Commonly used for multivitamin tablets and for antacids, antibiotics

A

Chewable Tablets

23
Q

Useful for children and elderly who is hvaing difficulty swallowing

A

Chewable Tablet

24
Q

Tablets are placed under the tongue and dissolved rapidly

A

Sublingual Tablet

25
Q

Tablets designed to dissolve slowly in the mouth between the cheek and gingiva

A

Buccal tablets

26
Q

Use of Sublingual and Buccal tablet

A

Suitable for drugs that does not absorbed very well in stomach
Avoid first pass metabolism

27
Q

Slow dissolving tablet prepared by molding or compression to produce local/systemic effect

A

Lozenges and Troches

28
Q

Molded Lozenge

A

pastilles

29
Q

Lozenge + Stick

A

Lollipop

30
Q

Compressed lozenges

A

Troches

31
Q

Use of Lozenges and Troches

A

Better patient compliance
Avoide First pass

32
Q

Tablets containing an organic acid and carbonate salt along with API, and dissolved in water

A

Effervescent Tablet

33
Q

Effervescent tablet composition

A

Tartaric Acid
Citric Acid
NaHCO3

34
Q

Advantages of Effervescent Tablet

A

Improves palatability and faster absorption

35
Q

Tablets containing large amounts of highly potent drug substances and supplied for Extemporaneous Compounding of the pharmacist

A

Dispensing tablet/Compounding Tablet

36
Q

Advantages of Dispensing tablet

A

Can extemporaneously prepared according to requirement of patient

37
Q

Soft, readily soluble tablets, used by physician in preparation of parenteral solution

A

Hypodermic Tablets

38
Q

Tablets prepared by molding and are very soft and disintegrate quickly

A

Molded tablet/tablet Triturates

39
Q

Drug product that alter the rate or timing of drug release

A

Modified Release Dosage Form

40
Q

Abrupt, uncontrolled release of a large amount of drug

A

Dose dumping

41
Q

Types of Modified Release Dosage Forms

A

a. Extended release (Controlled release, sustained release)
b. Deleayed release
c. Repeat Action
d. Targeted Release

42
Q

Dosage form that maintains the therapeutic blood or tissue levels of the drug for a prolonged period

Provides a prompt-desired effect followed by a gradual release of remaining amount

A

Extended release

43
Q

Releases the drug at a constant rate and provide plasma concentrations that remain invariant with time

A

Controlled-release

Follows Zero-order

44
Q

Releases an initial release of drug sufficient to provide a therapeutic dose after administration, then a gradual release over an extended period

A

Sustained release

Follow first-order
Affected by environment

45
Q

Designed to release the drug at a time other than promptly after administration

A

Deleayed release Dosage Forms

46
Q

Individual dose is released after administration, and second dose is released at intermittent intervals

A

Repeat Action

1st dose - Immediate release
2nd dose - delayed release

47
Q

Drug release is direct toward isolation or concentrating a drug in a body, tissue, or site for abs or action

A

Targeted-release

DDS (18 decks)

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