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DDS > Capsules > Flashcards

Capsules Flashcards

1
Q

Solid dosage form in which one or more medicinal &/or inert substances are enclosed within a small edible shell usually made of gelatin

A

Capsules

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2
Q

Gelatin is obtained by ____________ of ____ obtained from skin, white connective tissue, and bones of animals

A

Gelatin is obtained by partial hydrolysis of collagen obtained from skin, white connective tissue, and bones of animals

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3
Q

Two Types of Gelatin

A

Type A - Acid Hydrolysis
Type B - Alkali Hydrolysis

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4
Q

Gelatin Grade is specified by

A

Bloom Strength

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5
Q

Bloom Strength of HCG

A

200 - 250g

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6
Q

Bloom Strength of Soft Gelatin Capsuke

A

150 g

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7
Q

Hard Gelatin Capsule considered vegetarian and can be used by people with restriction on consuming animal-based product

A

Hydroxypropyl methylcellulose (HPMC)

or STARCH

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8
Q

Storage condition of Capsules

A

10°C - 25°C and 35% - 45% RH

or

15°C - 30°C and <70RH

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9
Q

Dry Filled Capsule

A

Hard Gelatin Capsule

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10
Q

Main components of HGC

A

Gelatin
Sugar
Water
Colorant
Sulfur dioxide 0.15%
Titanium Oxide - Opacifying agent

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11
Q

Moisture Content of HGC

A

12-16% or 13-16% moisture

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12
Q

Method of Preparation

EXTEMPORANEOUS

A

Punch Method

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13
Q

Dosage form of choice for clinical trials

A

Hard Gelatin Capsule

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14
Q

Capsule sizes fit for Human use

A

SIze 000 (largest) to 5 (smallest)

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15
Q

Powder capacity of size 000

A

650-2000 mg

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16
Q

Powder capacity of size 5

A

60 -130mg

17
Q

Capsule size for veterinary use

A

No 10. – No. 12

18
Q

Soft elastic capsule

A

Soft Gelatin Capsule

19
Q

contains non-aqueous liquids (vitamin e, cod liver oil, digoxin), suspensions, pastes, and dry solids

A

Soft Gelatin capsule

20
Q

Main components of Soft Gelatin Capsule

A

Gelatin - Type B
Water
Plasticizer (Glycerin, Sorbitol)
Methyl/Propyl Paraben
Titanium oxide
Colorant, Flavoring, Sweetening Agent

21
Q

Method of Preparation of SGC

A

Plate Process
Rotary Die Process

22
Q

Encapsulation Process of SGC

A
  1. Preparation of Formulation
  2. Filling
  3. Sealing
  4. Cleaning & Polishing
23
Q

Moisture content of SGC

A

6 - 10%

DDS (18 decks)

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