Liquid Flashcards

1
Q

Liquid preparations, that contain one or more chemical substances dissolved in a suitable solvent or mixture of mutually miscible solvents

A

Solutions

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2
Q

Advantages of Liquid Dosage Forms

A

Ideal for drugs that cannot be orally delivered
Delivery to the site of action is rapid
Ease of swallowing
A more uniform dosage form
Liquid dosage form of choice in certain conditions

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3
Q

Disadvantages of Liquid Dosage Forms

A

Liquid dosage forms are bulky
Udergo deterioration and loss of potency
Has water as an excellent medium for growth bacteria and mold

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4
Q

Most commonly used vehicle fo drug solutions

A

Water

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5
Q

Types of Water

A

Purified Water
Water for injection
Sterile Water for Injection
Bacteriostatic Water from Injection
Sterile Water for Inhalation
Sterile Water for Irrigation

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6
Q

Obtained by distillation, ion-exchange, reverse osmosis

A

Purified Water, USP

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7
Q

Purified Water, USP used in liquid dosage form, except ________ and ________ products

A

Purified Water, USP used in liquid dosage form, except parenteral and opthalmic products

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8
Q

Solvent used in large scale manufacture of injection

A

Water for Injection, USP

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9
Q

Water for Injection, USP is not ____ but should be ____

A

Water for Injection, USP is not sterile but should be pyrogen-free

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10
Q

Sterilized WFI

A

Sterile Water for Injection, USP

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11
Q

Solvent for reconstitution of multiple antibiotics

A

Sterile Water for Injection

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12
Q

Sterile Water for Injection with antimicrobial agent (benzyl alcohol)

A

Bacteriostatic Water for Injection

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13
Q

TF: Bacteriostatic Water for Injection can be used in neonates

A

FALSE
Bacteriostatic Water for Injection can NOT be used in neonates

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14
Q

SWFI that is not for parental or sterile dosage form

A

Sterile Water for Inhalation

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15
Q

SWFI for sterile irrigation, washing, rinsing, and dilution

A

Sterile Water for Irrigation

NOT FOR INJECTION
FOR IRRIGATION ONLY

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16
Q

Aqueous Solutions

A

Aromatic Water
Diluted Acids
Douches
Enemas
Mouthwashes
Gargles

17
Q

Clear, saturated aqueous solutions of volatile oils or other aromatic substances

A

Aromatic Water/Medicated Waters

18
Q

Use of Aromatic Water/Medicated Waters

A

Vehicle
Aq phase in suspension or emulsion

19
Q

Problem in Aromatic Water/Medicated Waters

A

Salting out – insoluble layer at top

20
Q

Methods of Preparation

A

Distillation/Cohobation
Solution Methid
Alternate Solution Method

21
Q

Universal method but not practical/economical

A

Distillation/Cohobation

22
Q

Distillation/Cohobation is used in preparation of

A

Orange Flower Water
Strong Rose Water
Hamamelis Water

23
Q

Method where volatile oil is admixed with water

A

Solution Method

24
Q

Method used in Chloroform Water

A

Solution method

25
Q

Method of preparation with dispersant (Talc)

A

Alternate Solution Method

26
Q

Method used in Cinnamon Water

A

Alternate Solution Method

27
Q

Aqueous solutions of concentrated acid dissolve in purified water of suitable strength **10% w/v **

A

Diluted Acids

(except Acetic Acid, 6%)

28
Q

Method used in preparation of Dil. Hydrochloric Acid, USP

Tx of achlorhydria

A

Diluted Acid

29
Q

Cleansing or antiseptic agent directed against a part or into cavity of the body

A

Douches

30
Q

Types of Douches

A

Eye douche
Pharyngeal douche
Nasal douche
Vaginal douche

31
Q

Rectal solutions employed mainly to evacuate the bowel (evacuation enema) or to affect a local or systemic disease by absorption (retention enema)

A

Enemas / Clyster

32
Q

Sodium phosphates enema (fleet enema)

A

Evacuation Enema

33
Q

Retention Enemas

A

Hydrocortisone Enema - Local
Aminophylline Enema - Systemic
Sulfasalazine Enema

34
Q

Solutions that are used to cleanse the mouth or treat diseases of the oral mucous membrane

A

Mouthwashes

35
Q

Types of mouthwashes

A

Cosmetic - reduce bad breath
Therapeutic - reduce plaque, gingivits, dental caries, stomatitis

36
Q

Used to diagnose oral cancer and lesions

A

Toluidine Blue Rinse

37
Q

Used for treating pharynx and nasopharynx by forcing from lungs through solution held in throat

A

Gargles