Semi-Solid

Question 1

Semisolid preparations containing one or more medicinal agents dissolved or dispersed in either a w/o or o/o emulsion or in water-washable base

Answer 1

Cream

Question 2

Preferred by patients and physicians because of ease of spreadability and removal.

Answer 2

Creams

Question 3

Examples of Creams

Answer 3

Vanishing Creams
Cold Cream

Question 4

W/O Emulsion

Answer 4

Cold Cream

Question 5

Components of Cold Cream

Answer 5

White wax
Spermaceti
Almond Oil or Mineral Oil

Almond Oil - better emollient base
Mineral Oil - Mores stable cold cream

Question 6

O/W Emulsion

Answer 6

Vanishing Cream

Question 7

Contains large percentage of water and humectant (Propylene glycol, PEG)

Answer 7

Vanishing Cream

Question 8

Forms a thin film when the water evaporates

Answer 8

Stearic Acid in Vanishing Cream

Question 9

Semi-solid with high content of solids (>25%), stiifer, and less penetrating compared to ointment

Answer 9

Paste

Question 10

Solid or semisolid adhesive masses spread on a backing of paper, fabric, moleskin or plastic

Answer 10

Plasters

Question 11

Uses of Plaster

Answer 11

Prolong contact of drug to site of absorption
Provide protection or mechanical support at site

Question 12

Example of Plaster

Answer 12

Salicylic Acid Plaster (10 - 40%) - Keratolytic

Question 13

Plastic masses applied on skin with a fine brush

Answer 13

Glycerogelatin

Question 14

Composition of Glycerogelatin

Answer 14

40% Glycerin
15% Gelatin
15% Water
10% Active ingr

Question 15

Example of Glycerogelatin

Answer 15

Zinc Gelatin Boot – treatment of varicose ulcers