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DDS > Solid Dosage Forms > Flashcards

Solid Dosage Forms Flashcards

1
Q

Intimate mixtures of finely divided drugs or chemicals in dry form which may be used internally or externally

A

Powder

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2
Q

Advantages of Powders

A

flexibility in compounding
good stability
rapid dispersion of ingredients
relatively dry & devoid of moisture

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3
Q

Disadvantages of Powders

A

Inaccuracy of dose
Not suitable for dispersing deliquescent and hygroscopic drugs
Time consuming Preparation
Not suitable for unpleasant tasting drugs

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4
Q

Animal and Vegetable Drugs
Sieve

A

Very coarse – no. 8
Coarse – no. 20
Moderately coarse – no. 40
Fine – no. 60
Very fine – no. 80

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5
Q

Chemical
Sieve

A

Coarse – no. 20
Moderately coarse – no. 40
Fine – no. 80
Very fine – no. 120

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6
Q

Reduction in particle size of solid to a finer state

A

Comminution

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7
Q

Methods of Comminution

A

Trituration
Levigation
Pulverization by Intervention

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8
Q

Reducing particle size with use of Mortar and pestle

A

Trituration

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9
Q

Types of Mortar

A

Glass
Wedgewood
Porcelain

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10
Q

Glass Mortar

A

Smooth surface
Non-porous
Used for highly colored materials and dyes

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11
Q

Wedgewood Mortar

A

Tough surface
Porous
Used for Crystalline Solids

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12
Q

Porcelain Mortar

A

Tough surface
Porous
Used for soft aggregates and crystals

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13
Q

Commonly used in small scale preparation of ointments & suspensions to reduce particle size & grittiness of the added products

Formation of paste by addition of non-solvent (levigating agent)

A

Levigation

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14
Q

Levigating agents

A

mineral oil
glycerin
propylene glycol

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15
Q

Addition of volatile substances to gummy compounds

A

Pulverization by intervention

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16
Q

Camphor + Alcohol
Iodine Crystals + Ether

A

Pulverization by Intervention

17
Q

Mixing or Blending

A

Spatulation
Trituration
Geometric Dulution
Sifting
Tumbling

18
Q

Blend small amounts of powders on a sheet of paper/tile
use of spatula; not for potent substances

A

Spatulation

19
Q

Spatulations is used for mixing

A

Small amounts of powders
Same densities of powders
Solid substances that liquefy or form eutectic mixtures

20
Q

Involves direct rubbing or grinding of hard powder in a mortar and pestle

A

Trituration

21
Q

Addition of equal volume of diluent to potent substances

A

Geometric Dilution

22
Q

Powders are mixed by passing through sifters

Not for potent substances

A

Sifting

23
Q

This process result in a light, fluffy product and useful for powders that resist mixing by trituration

A

Sifting

24
Q

A process of mixing powders by shaking or rotating in a closed container

A

Tumbling

25
Q

This method is used when two or more powders have considerable density differences

A

Tumbling

26
Q

Classification of Powders

A

1. Bulk Powder
* Oral Powders
* Dentrifices
* Dusting Powders
* Douche Powders
* Insufflators
* Triturations

2. Divided

27
Q

Finely divided powders or effervescent granules, dissolved in water or mixed with soft foods

A

Oral Powder

28
Q

Exist in liquid, pwder, or paste form; used for oral hygiene

A

Dentirifices

29
Q

Dentrifices + Fluoride compounds

A

protect teeth against dental caries

30
Q

Intended to be dissolved in tepid water before use

A

Douch powders

31
Q

Antiseptic or cleansing agents for a body cavity, commonly used for vagina

A

Douche Powder

32
Q

Also known as Conspergents

A

Dusting powder

33
Q

Locally applied non-toxic preparations intended to have no systemic action

A

Dusting powder

34
Q

Finely divided powders, introduced to body cavities using insufflatos or powder blower

A

Insufflations

35
Q

Dilution of potent drugs

1:10 dilutions

A

Triturations

36
Q

Chartula/Chartulae

A

Divided Powders

37
Q

Dispensed in individual doses usually in folded papers

A

Divided powders

38
Q

Divided powders are prepared by

A
  • Weighing individuallly
  • Block and divided method (nonpotent)
39
Q

Types of Powder paper

A

White Bond Paper – opaque paper with no moisture resistance
Glassine Paper – glazed transparent moisture-resistant paper
Vegetable Parchment – thin, semi-opaque, moisture-resistant paper
Waxed Paper – transparent waterproof paper; suitable for deliquescent and hygroscopic drugs

DDS (18 decks)

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