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Pharma A > Sympathetics > Flashcards

Sympathetics Flashcards

1
Q

Directly interact with and activate adrenoreceptors

A

Cathecolamine

Epinephrine

Norepinephrine

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2
Q

Displaces stored catecholamine

A

Tyramine

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3
Q

Inhibits reuptake of released catecholamine

A

Cocaine

Trycyclic antidepressant

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4
Q

What are the 3 components of the G protein mediated response

A

GPCR

G protein

Effector protein

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5
Q

Mixed type of alpha and beta agonist

A

Norepinephrine

Epinephrine

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6
Q

Alpha agonist that is more on A1

A

Phenylephrine

Methoxamine

Clonidine

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7
Q

Alpha agonist more on A2

A

Methynorepinephrine

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8
Q

Beta agonist that are more b1

A

Dobutamine

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9
Q

Beta agonist B1 = B2

A

Isoproterenol

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10
Q

Dopamine agonist D1 = D2

A

Dopamine

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11
Q

Dopamine agonist D1 more than D2

A

Fenoldopam

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12
Q

Vascular smooth muscle

Heart

Pupil

A1

A

Contraction

Dilates pupil

Increase force of contraction

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13
Q

Platelets and fat cells

A2

A

Aggregation

Inhibits lipolysis

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14
Q

B1

Heart

JG cells

A

Increase force and rate

Increase release of renin

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15
Q

B2

Respiratory

Uterine

Liver

A

SM relaxation

Glycogenolysis

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16
Q

B3

Bladder

Fat cells

A

Relaxes destrussor

Lipolysis

17
Q

D1

Smooth muscle

A

Dilates renal blood vessel

18
Q

Epinephrine

Activation of A1 B1 b2

A

Alpha receptor - vasoconstriction

B1 receptor - Cardiac stimulation

B2 receptor - Bronchodilation

19
Q

Uses of terbutaline and ritodrine

A

Prevent premature labor

Terbutaline can be used for asthma

20
Q

Usage for phenylephrine

A

Mydriatic

Increase BP

Decongestant

21
Q

Clonidine and methyldopa effects

A

Decrease BP through actions in the CNS

22
Q

Amphetamine variant

Used among children with ADHD

A

Methylphenidate

23
Q

Usefullness in adhd

A

Modafinil

24
Q

This is a NE uptake inhibitor

Used in adhd

A

Atoxmoxetine

25
Q

Used for pharmacologic stress test

A

Dobutamine

26
Q

A1 > A2 alpha antagonist

A

Prazosin

Terazosin

Phenoxybenzamine

27
Q

Mixtes antagonist

A

Labetalol

Carvedilol

28
Q

Beta antagonist B1 > B2

A 
Metoprolol 
Acebutolol
Betaxolol
Atenolol
Esmolol
29
Q

Beta 1 = Beta 2 antagonist

A

Propanolol

Carteolol

Timolol

30
Q

B2 > B1 antagonist

A

Butoxamine

Pharma A (19 decks)

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