Reproductive

Question 1

Large surface area yields rapid absorptiob

Answer 1

Micronized

Question 2

Receptors found in uterus, vagina, ovaries and mammary glands and prostate

Answer 2

ErA

Question 3

Clinical use of synthetic combination of contraceptive

Answer 3

Regulate menses
Amenorrhea like PCOS
Relieves dymenorrhea
Hypogonadisn
Menopausal hormonal therapy

Question 4

Uses of synthetic estrogen alone

Answer 4

Hirsutism
Relieve mild to moderate depression
Given to prevent pregnancy
Palliative treatment for prostate CA

Question 5

SERMS

Answer 5

Tamoxifen
Raloxifene
Toremifene
Bazedoxifene

Question 6

Non steroidal anti estrogen

Answer 6

Clomiphene

Fulvestrant

Question 7

Given for a precursor for endometrial cancer

Answer 7

Tamoxifen

Question 8

Indicated for px at risk of breast CA

Answer 8

Raloxifene

Question 9

Increases LH and FSG amplitude pulses

Answer 9

Clomiphene

Question 10

Increases intracellular proteolytic degradation of era and erb

Answer 10

Fulvestrant

Question 11

Drug that displaces warfarin

Answer 11

Tamoxifen

Question 12

If the px has er negative what drug that is not given

Answer 12

Tamoxifen

Question 13

Prevention and treatment of osteoporosis

Answer 13

Raloxifen

Question 14

CI or precautions for SERMS

Answer 14

VTE
Stroke
Heavy smoker

Question 15

Clinical use of clomiphene citrate

Answer 15

Ovulation induction
Abnormal uterine bleeding
Endometrial hyperplasia
PCOS

Question 16

CI for clomiphene acetate

Answer 16

Ovarian enlargement

Visual disturbance

Question 17

21 carbon progesterone has what

Answer 17

Antagonize aldosterone

Question 18

Norethindone
Norgestrel
Desogestrel binds to what

Answer 18

SHBG

Albumin

Question 19

Used in management of paraphilia

Answer 19

Depo-provera

Question 20

Anti progesterone drugs

Answer 20

Mifeprestone

Ulipristal acetate

Question 21

Action of ulipristal acetate

Answer 21

Anti proliferative effect on the endometrium

Inhibit ovulation

Question 22

Therapeutic use of ulipristal acetate

Answer 22

Emergency contraceptive in rape

Question 23

First generation estrogen

Answer 23

Femenal

Nordiol

Question 24

Second generation estrogen and progesterone

Answer 24

Microgynon
Micropil
Nordette
Trinordiol
Logynon

Question 25

Third generation pill

Answer 25

``` Gynera Meliane Marvelon Mercilon Gracial Minulet ```

Question 26

Fourth gen pill

Answer 26

Qlaira Yasmin Yaz

Question 27

Decreased incidences with progesterone alone

Answer 27

Ovarian Endometrial Benign fibrocystic breast disease

Question 28

Relative contraindications for progesterone

Answer 28

``` Smoking Controlled htn Fibroid tumor Dm History of dyslipidemia Sickle cell Active gall bladder disease More than 50yr Elective surgery Migraine ```

Question 29

Used for endometriosis

Answer 29

Danazol

Question 30

Clinical use of cyproterone acetate

Answer 30

``` Adjunct in prostate ca Precoccious puberty Masculinzation and acne Reverse sexuality Anti androgenic effect ```

Question 31

Used for prostatic ca with gnrh And excess androgen in women

Answer 31

Flutamide Bilcalutamide Nilutamide Enzalutamide

Question 32

Clinical uses of finasteride and dutasteride

Answer 32

BPH Prostatic CA Hirsutism Baldness