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Pharma A > Reproductive > Flashcards

Reproductive Flashcards

1
Q

Large surface area yields rapid absorptiob

A

Micronized

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2
Q

Receptors found in uterus, vagina, ovaries and mammary glands and prostate

A

ErA

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3
Q

Clinical use of synthetic combination of contraceptive

A 
Regulate menses
Amenorrhea like PCOS
Relieves dymenorrhea
Hypogonadisn
Menopausal hormonal therapy
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4
Q

Uses of synthetic estrogen alone

A

Hirsutism
Relieve mild to moderate depression
Given to prevent pregnancy
Palliative treatment for prostate CA

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5
Q

SERMS

A

Tamoxifen
Raloxifene
Toremifene
Bazedoxifene

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6
Q

Non steroidal anti estrogen

A

Clomiphene

Fulvestrant

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7
Q

Given for a precursor for endometrial cancer

A

Tamoxifen

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8
Q

Indicated for px at risk of breast CA

A

Raloxifene

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9
Q

Increases LH and FSG amplitude pulses

A

Clomiphene

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10
Q

Increases intracellular proteolytic degradation of era and erb

A

Fulvestrant

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11
Q

Drug that displaces warfarin

A

Tamoxifen

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12
Q

If the px has er negative what drug that is not given

A

Tamoxifen

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13
Q

Prevention and treatment of osteoporosis

A

Raloxifen

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14
Q

CI or precautions for SERMS

A

VTE
Stroke
Heavy smoker

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15
Q

Clinical use of clomiphene citrate

A

Ovulation induction
Abnormal uterine bleeding
Endometrial hyperplasia
PCOS

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16
Q

CI for clomiphene acetate

A

Ovarian enlargement

Visual disturbance

17
Q

21 carbon progesterone has what

A

Antagonize aldosterone

18
Q

Norethindone
Norgestrel
Desogestrel binds to what

A

SHBG

Albumin

19
Q

Used in management of paraphilia

A

Depo-provera

20
Q

Anti progesterone drugs

A

Mifeprestone

Ulipristal acetate

21
Q

Action of ulipristal acetate

A

Anti proliferative effect on the endometrium

Inhibit ovulation

22
Q

Therapeutic use of ulipristal acetate

A

Emergency contraceptive in rape

23
Q

First generation estrogen

A

Femenal

Nordiol

24
Q

Second generation estrogen and progesterone

A 
Microgynon
Micropil
Nordette
Trinordiol
Logynon
25
Q

Third generation pill

A 
Gynera
Meliane
Marvelon
Mercilon
Gracial
Minulet
26
Q

Fourth gen pill

A

Qlaira
Yasmin
Yaz

27
Q

Decreased incidences with progesterone alone

A

Ovarian
Endometrial
Benign fibrocystic breast disease

28
Q

Relative contraindications for progesterone

A 
Smoking
Controlled htn
Fibroid tumor
Dm
History of dyslipidemia
Sickle cell
Active gall bladder disease
More than 50yr
Elective surgery
Migraine
29
Q

Used for endometriosis

A

Danazol

30
Q

Clinical use of cyproterone acetate

A 
Adjunct in prostate ca
Precoccious puberty
Masculinzation and acne
Reverse sexuality
Anti androgenic effect
31
Q

Used for prostatic ca with gnrh

And excess androgen in women

A

Flutamide
Bilcalutamide
Nilutamide
Enzalutamide

32
Q

Clinical uses of finasteride and dutasteride

A

BPH
Prostatic CA
Hirsutism
Baldness

Pharma A (19 decks)

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