Anemia Flashcards
Binds iron in the plasma and this is used for erythropoiesis
Transferrin
Triggers release of iron from storage sites while high levels prevent iron release
Low level of hepcidin
Elemental iron per tab is 65mg
Ferrous sulfate, hydrated 325mg
ferrous sulfate dessicated
200mg
Elemental iron preparation of ferrous gluconate
36mg
How many mg of elemental iron per day for rapid correction
200-400mg
Common side effects of oral iron
GI upset Constipation Diarrhea Nausea Blackish stool
When do you give parenteral iron
Intolerance of side effect
Malabsorption and inflammatory bowel disease
Severe chronic anemia
Adverse effects of iron dextran
Headache Fever Joint pains Nausea vomiting Back pain Flushing and urticaria Bronchospasm Anaphylaxis
Major dietary and storage form of folate
N methyltetrahydrofolate
What is increased as a marker for vitamin b12 deficiency
Serum homocysteine
Daily absorption of folic acid
50-200 mcg
300-400 pregnant women
Clinical use of folic acid
Megaloblastic anemia
Treatment methotrexate, trimethoprim and pyromethamine
Hgb levels for EPO therapy
Less than 10 g/dl
Toxicity of epo
Hypetension
Thromboembolic events with more than 11 hgb
Transient influenza like symptoms
Binds to specific progenitor of myeloid
Lenograstim
