Gastrointestinal Drugs

Question 1

This antacid reacts rapidly with HCL

Answer 1

Sodium Bicarbonate

Question 2

Side effects of Aluminum or Magnesium hydroxide

Answer 2

Aluminum - Constipation

Magnesium - Diarrhea

Question 3

What antacid can lead to hypercalcemia, renal insufficiency and metabolic alkalosis

Answer 3

Calcium carbonate

Question 4

What are the histamine blockers that go through first pass effect

Answer 4

Cimentidine
Ranitidine
Famotidine

Question 5

Clinical use of H2 blocker

Answer 5

GERD
Peptic Ulcer disease
Non ulcer dyapepsia
Prevention of bleeding

Question 6

AE of cimentidine

Answer 6

Mental status change
Gynecomastia
Galactorrhea
Impotence

Question 7

Treatment of acid peptic disease

Answer 7

Proton Pump Inhibitors

Question 8

When do you administers PPI o

Answer 8

On an empty stomach

Question 9

MoA of PPI

Answer 9

Inhibit both acid fasting and meal stimulated secretion

Question 10

AE of PPI

Answer 10

CAR infection
Nosocomial pneumonia
Enteric infection

Question 11

What PPI may inhibit warfarin,diazepam and phenytoin

Answer 11

Omeprazole

Question 12

This ppi enhances clearance of theophylline

Answer 12

Lansoprazole

Question 13

Has limited solubility, breaking down into sucrose sulfate and aluminum salt

Answer 13

Sucralfate

Question 14

Used for prevention of traveler’s diarrhea

Answer 14

Bismuth compounds

Question 15

What is now used for acute large bowel distention or oglivie’s syndrome

Answer 15

Neostigmine

Question 16

Potent anti nausea and anti emetic action

Answer 16

Dopamine antagonist

Metoclopromide
Domperidone

Question 17

This drug has extrapyramidal effects

Answer 17

Metoclopromide

Question 18

Bulk forming laxative

Answer 18

Psyllium
Methycellulose
Polycarbophil

Question 19

AE of bulk forming stool

Answer 19

Bloating

Flatus

Question 20

Stool softeners

Answer 20

Docusate
Glycerin suppository
Mineral oil

Question 21

AE of stool softeners

Answer 21

Impair absorption of ADEK

Question 22

Commonly used osmotic laxative

Answer 22

Magnesium hydroxide

Milk of magnesia

Question 23

Sugars that prevent or treat chronic constipation

Answer 23

Sorbitol

Lactulose

Question 24

Given before endoscopy

Answer 24

Balanced PEG

Question 25

These drugs may decrease diarrhea by excess fecal bile acids

Answer 25

Colestyramine
Colestipol
Colesevelam

Question 26

AE of somatostatin

Answer 26

Stearrothrea

Question 27

Serotonin receptor antagonist activate afferwnt pain sensation

Answer 27

Alosetron

Question 28

Used for severe IBS with predominant diarrhea

Answer 28

Alosetron

Question 29

Given with severe ibs with predominant constipation

Answer 29

Tegaserod

Question 30

What is the pathway used by antiemetic agents

Answer 30

Nucleus tractus solitarius

Question 31

Clinical usage of serotonin antagonist

Answer 31

Chemotheraphy induced nausea and vomting

Post operative and radiation nausea and vomiting

Question 32

This anti emetic drugs can cross the bbb

Answer 32

Neurokinin antagonist

Apreripant
Fosaprepitant

Question 33

Antipsychotic drug that is potent antiemetic and sedative

Answer 33

Phenothiazines

Question 34

Central dopaminergic blockade

Answer 34

Droperidol

Question 35

Treatment of emesis due to chemotherapy

Answer 35

Diphenhydramine

Question 36

Best agent used for the prevention of motion sickness

Answer 36

Hyoscine

Scopolamine

Question 37

Drug used to reduced anticipatory vomiting by anxiety

Answer 37

Lorazepam

Diazepam

Question 38

Mesalamine compounds

Answer 38

Rowasa or canasa (suppositories)

Question 39

Given for crohn’s disease

Moderate to severe active inflammatory bowel disease

Answer 39

glucocorticoid

Budesonide

Question 40

Severe crohn’s disease

Anti integrin therapy

Answer 40

Natalizumab