CHF And Diuretics

Question 1

With reduced mechanical pumping action contractility and reduced ejection fraction

Answer 1

Systolic

Question 2

Stiffening and loss adequate relaxation

Answer 2

Diastolic

Question 3

Subjective sign of right ventricular failure

Answer 3

Generalized edema

Question 4

What is added at anytime to reduce symptoms and prevent hospitalization

Answer 4

Digoxin

Question 5

What is recommended for patients with sign of congestions

Answer 5

Diuretics

Question 6

Recommended for patients with advanced HF with or after MI in the presence of symptoms or DM with a low EF or patients with Class 2

Answer 6

Aldosterone antagonist

Question 7

Bed rest and restricted physical activities are indicated with

Answer 7

Acute exacerbation

Question 8

May be given in mild chronic failure

Answer 8

Thiazides

Question 9

What loop diuretics has vasodilation decrease renal vascular resistance

Answer 9

Furosemide

Question 10

This reduce remodeling and sympathetic excess in chronic HF

Answer 10

ACEi

Question 11

What drug causes cough and renal damage in the fetus and is contraindicated in pregnant women

Answer 11

ACEi

Question 12

What beta blockers can prolong life in chronic HF that are given orally

Answer 12

Carvedilol

Metoprolol

Question 13

This toxicity causes worsening of HF, av blockade, hypotension and sedation

Answer 13

beta blockers

Question 14

This drug is beta 1 selective agonist that is given parenterally for severe acute HF

Answer 14

Dobutamine

Question 15

Not beta 1 selective inotrope

Answer 15

Dopamine

Question 16

This drug blocks NA K ATPase and increase intracellular sodium

Answer 16

Digoxin

Question 17

What is the common digoxin toxicity

Answer 17

Cardiac Arrythemia

Question 18

Optimal dose for digoxin

Answer 18

0.5 to 1ng/ml

Question 19

3 drugs that lower digoxin levels in the serum concentration

Answer 19

Rifampin

St. John Wort

Sulfasalazine doses >2 g/d

Question 20

What are the classifications are contraindicated for wolff parkinson white syndrome

Answer 20

Digoxin, beta blocker, calcium channel blocker, adenosine

Question 21

This drug is angiotensin receptor neprilysin inhibitor

Answer 21

Lcz6956

Question 22

This drug act like glycoside but also facilitates sequestration of calcium ions by the sarcoplasmic reticulum

Answer 22

Istaroxamine

Question 23

This prevents hyponatremia in SIADH

Answer 23

Demeclocycline

Question 24

Like conivaptan but more selective for V2 receptors

Answer 24

Tolvaptan

Question 25

What drug is a prototype of loop diuretics

Answer 25

Ethacrynic acid

Question 26

MoA of Loop Diuretics

Answer 26

Blocka Na K Cl symporter in TAL

Question 27

This drug is excreted by the biliary system

Answer 27

Indapamide

Question 28

Toxicities in Thiazide

Answer 28

Hyper lipidemia Impotence Carbohydrate tolerance

Question 29

For pituitary deficiency diabetes but not nephrogenic diabetes insipidus

Answer 29

Vasopressin Desmopressin