Parasympathetic

Question 1

Choline is brought to the presynaptic terminal by what kind of transporter

Answer 1

Choline Transporter (CHT)

Question 2

CHT is inhibited by what agent

Answer 2

Hemicholinium

Question 3

What catalyzes the acetylCoA and Choline

Answer 3

Choline Acetyltransferase CHAT

Question 4

What inhibits acetylcholine to be store in the vesicle

Answer 4

Vesamicol

Question 5

What inhibits acetylcholine to the synaptic cleft

Answer 5

Botulinum

Question 6

What is the cathecolamine neurotransmitter precursor for adrenergic transmission

Answer 6

Tyrosine

Question 7

How is tyrosine converted to dopamine

Answer 7

Tyrosine kinase

Question 8

What inhibits tyrosine kinase

Answer 8

Metyrosine

Question 9

What inhibits dopamine to be stored in the vesicle

Answer 9

Reserpine

Question 10

How is dopamine converted to Norepi

Answer 10

Dopamine beta hydroxylase

Question 11

What inhibits Norepi to be exocytosed

Answer 11

Guanithidine

Bretyllium

Question 12

What inhibits the reuptake of NE back to the presynaptic cell

Answer 12

Cocaine

Amphetamines

Tricyclic antidepressants

Question 13

Can cause direct transmitter release from noradrenergix endings in a non calcium dependent process and not via vesicular fusion and exocytosis

Answer 13

Tyramine

Amphetamines

Ephedrine

Question 14

N1 or NM has what kind of response

Answer 14

Endplate depolarization

Skeletal muscle contraction

Question 15

Types of choline esters

Answer 15

Acetylcholine

Meta choline

Carbachol

Betanechol

Question 16

Which choline acts on both cholinoreceptors

Answer 16

Acetylcholine

Question 17

What choline esters that are non susceptible to acetylcholinesterase

Answer 17

Carbachol

Betanechol

Question 18

which choline water acts on muscarinic receptor

Answer 18

Betanechol

Question 19

What are example of cholinomimetix alkaloids that are tertiary amines

Answer 19

Pilocarpine

Nicotine

Lobeline

Question 20

Bonding of what type of agonist would lead to activation of IP3 and DAG

Answer 20

M1

M3

M5

Question 21

Parasympathetic effect on the eyes

Answer 21

Miosis

Accommodation

Opens outflow for aqueous humor

Question 22

Parasympathetic effect on the CVS

Answer 22

Decrease peripheral vascular resistance

Decrease in heart rate

Question 23

What do you give to counteract the pilocarpine ineffective of hypotension to hypertension

Answer 23

Atropine

Question 24

GIT and GUT are controlled by what muscarinic receptor

Answer 24

M2

M3

Question 25

It is a simple alcohol with quarternary ammonium group Used in MG, ileus and arrhythmias

Answer 25

Edrophonium

Question 26

This is carbamic acid used in glaucoma

Answer 26

Physostigmine

Question 27

What are examples of carbamic acid esters of alcohol that are quarternary ammonium

Answer 27

Neostigmine Pyridostigmine

Question 28

Organophosphate that are irreversible

Answer 28

Echotiopate Sarin Parathion Malathion

Question 29

Effect of cholinesterase inhibitors on the CVS

Answer 29

Decrease heart rate Decrease cardiac output Decrease impulse conduction

Question 30

Edrophonium effect on modest dosage on the cvs

Answer 30

Modest bradycardia Cadiac output reduction Increase vascular resistance

Question 31

Post operative ileus and congenital mega colon

Answer 31

Neostigmine Betanechol

Question 32

Postoperative and post partum urinary retention

Answer 32

Neostigmine

Question 33

Gerd

Answer 33

Betanechol

Question 34

Sjorgen syndrome

Answer 34

Pilocarpine

Question 35

Reversal of surgically induced neuromuscular blockade

Answer 35

Neostigmine Edrophonium

Question 36

For alzehemier's disease

Answer 36

Donepezil Galantamine Rivastigmine

Question 37

Protection agents chemical warfare

Answer 37

Pyridostigmine