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Pharma A > Antihypertensive And Angina > Flashcards

Antihypertensive And Angina Flashcards

1
Q

What are the central acting sympathoplegic drugs

A

Methyldopa (aldomet)
Clonidine (catapres)
Guanfacine
Guanbenz

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2
Q

This is useful for opoid or nicotine dependent

A

Clonidine

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3
Q

Ganglion blocking agent

A

Trimethapan (arfonad)

Mecamylamine (inversine)

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4
Q

Mechanism of action for ganglion blocking agent

A

Blocks both sympathetic and parasympathetic

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5
Q

Adrenergic neuron blocking agent

A

Guanetidine (ismelin)

Reserpine

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6
Q

This prevents norepinephrine release from nerve terminals

A

Guanetidine (ismelin)

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7
Q

Mechanism of Action for Guanethidine

A

Gradual depletion of NE in the nerve ending

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8
Q

This disrupts norepinephrine vesicular storage

A

Reserpine

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9
Q

What are the neurotransmitter that are being depleted by reserpine

A

NE

Dopamine

Serotonin

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10
Q

This depress the asanas function centrally and peripherally

A

Reserpine

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11
Q

Alpha adrenoreceptor antagonist

A

Prazosin (minipress)

Terazosin (hytrin)

Doxazosin (cardura)

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12
Q

This beta blocker is used during resting bradycardia and a reduction in the heart rate during exercise

A

Propranolol

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13
Q

This used for patients with hypertension with asthma, diabetes or peripheral vascular disease

A

Metoprolol

Atenolol

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14
Q

These drugs are beneficial for patients with bradyarrhythmias or peripheral vascular disease

A

Pindolol

Acebutolol

Penbutolol

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15
Q

This is used to treat hypertension of pheochromocytoma and hypertension emergency

A

Labetalol

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16
Q

This drug is useful in patients with both heart failure and hypertension

A

Carvedilol

17
Q

This is highly selective beta 1 blocking effects thus its effect is not mediated by alpha blockade

A

Nebivolol

18
Q

Used for management of intraoperative and postoperative and sometimes emergency hypertension

A

Esmolol

19
Q

These drugs causes hyerpolarization of smooth muscle membranes through opening of potassium channels

A

Minoxidil

Diazoxide

20
Q

What drug cause the activation of dopamine receptors

A

Fenoldopam

21
Q

What are the direct acting vasodilator

A

Fenoldopam

Hydrazaline

22
Q

How is Fenoldopam metabolized in the liver

A

conjugation

23
Q

How is Hydrazaline metabolized in the liver

A

Acetylation

24
Q

What is a renin inhibitor

A

Aliskiren

25
Q

What is a phosphorous containing ACE inhibitors

A

Fosinorpil

26
Q

Longest acting medication for angina

A

Pentaerytriol tetranitrate

PETN

27
Q

What are the keys in the activation and release of nitric oxide

A

ALDH 2 and 3

Pharma A (19 decks)

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