Antihypertensive And Angina Flashcards
What are the central acting sympathoplegic drugs
Methyldopa (aldomet)
Clonidine (catapres)
Guanfacine
Guanbenz
This is useful for opoid or nicotine dependent
Clonidine
Ganglion blocking agent
Trimethapan (arfonad)
Mecamylamine (inversine)
Mechanism of action for ganglion blocking agent
Blocks both sympathetic and parasympathetic
Adrenergic neuron blocking agent
Guanetidine (ismelin)
Reserpine
This prevents norepinephrine release from nerve terminals
Guanetidine (ismelin)
Mechanism of Action for Guanethidine
Gradual depletion of NE in the nerve ending
This disrupts norepinephrine vesicular storage
Reserpine
What are the neurotransmitter that are being depleted by reserpine
NE
Dopamine
Serotonin
This depress the asanas function centrally and peripherally
Reserpine
Alpha adrenoreceptor antagonist
Prazosin (minipress)
Terazosin (hytrin)
Doxazosin (cardura)
This beta blocker is used during resting bradycardia and a reduction in the heart rate during exercise
Propranolol
This used for patients with hypertension with asthma, diabetes or peripheral vascular disease
Metoprolol
Atenolol
These drugs are beneficial for patients with bradyarrhythmias or peripheral vascular disease
Pindolol
Acebutolol
Penbutolol
This is used to treat hypertension of pheochromocytoma and hypertension emergency
Labetalol
This drug is useful in patients with both heart failure and hypertension
Carvedilol
This is highly selective beta 1 blocking effects thus its effect is not mediated by alpha blockade
Nebivolol
Used for management of intraoperative and postoperative and sometimes emergency hypertension
Esmolol
These drugs causes hyerpolarization of smooth muscle membranes through opening of potassium channels
Minoxidil
Diazoxide
What drug cause the activation of dopamine receptors
Fenoldopam
What are the direct acting vasodilator
Fenoldopam
Hydrazaline
How is Fenoldopam metabolized in the liver
conjugation
How is Hydrazaline metabolized in the liver
Acetylation
What is a renin inhibitor
Aliskiren
