Supplements & Vitamins Flashcards
St. John’s Wort induces which CYP enzymes
3A4
2C19
2C9
1A2
St. John’s Wort Concerns???
Serotonergic agent:
- do not use with MAOi or linezolid
- caution with other serotonergic drugs
Photosensitivity
Lowers seizure threshold: caution use with
- bupropion
- quinolones
- tramadol
- penicillin
- carbapenems
Sooooo many DDI
Supplements that cause increased bleed risk
The 5 G’s
- Garlic
- Ginger
- Gingko
- Ginseng
- Glucosamine
Fish oils (high dose)
Vitamin E
Dong quai
Willow bark
Supplements with risk of hepatotoxicity
Black cohosh
Kava
Supplements with risk for cardiac toxicity
Bitter orange
Yohimbe
Caffeine
Supplements used for: anxiety
valerian
passion flower
kava
St. John’s Wort
Supplements used for: depression
St. John’s wort
SAMe
Valerian
5-HTP
Supplements used for: ADHD
omega 3 fatty acids
Supplements used for: cold sores
L-lysine
Supplements used for: cold & flu
Echinacea
Zinc
Vitamin C
Supplements used for: diabetes
alpha lipoic acid
chromium
cassia cinnamon
Supplements used for: dyslipidemia
red yeast rice
omega 3 fatty acids
Supplements used for: dyspepsia
calcium
magnesium
Supplements used for: energy/weight loss
bitter orange
caffeine
Guarana
Supplements used for: ED
ginseng
L-arginine
Yohimbe
Supplements used for: HF
CoQ10
Hawthorn
Omega 3 fatty acids