Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology - for VIVAs > Sulfonylureas > Flashcards

Sulfonylureas Flashcards

1
Q

What class of drug is gliclazide?

A

Sulfonylurea.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Describe the mechanism of action of sulfonylureas.

A

Stimulates insulin secretion from functional pancreatic beta cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the pharmacokinetic properties of gliclazide?

A

Administered orally - good bioavailability (80%)

Protein-bound - volume of distribution approx 20L

Hepatic metabolism to inactive metabolites

Half-life approx 12hrs

Predominantly renally excreted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the potential adverse effects of gliclazide?

A

Hypoglycaemia.

GI upset: N, V, D, abdo pain. Rash / pruritis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Pharmacology - for VIVAs (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions