Naloxone Flashcards
1
Q
What is the mechanism of action of naloxone?
A
Pure opioid antagonist. Binds to mu-opioid receptors.
2
Q
What is the time of onset, and duration of action, of naloxone when administered IV?
A
Time of onset 1-2 minutes.
Duration of action 1-2 hours.
3
Q
What problems may be associated with naloxone administration?
A
Opioid withdrawal.
Resedation.
4
Q
How can the adverse outcomes of naloxone administration be avoided?
A
Small doses, titrated to effect.
Route of administration.
Infusion.
