Opioids Flashcards
1
Q
Describe the pharmacokinetics of oxycodone.
A
Oral administration. Well absorbed orally.
High Vd. Less first pass metabolism than morphine. Hepatically metabolised. Has active metabolites.
(bold + 1 to pass)
2
Q
What adverse effects might you anticipate from giving oxycodone?
A
Sedation, respiratory depression, nausea and vomiting, hypotension, dysphoria, pruritis
(3 to pass)
3
Q
When prescribing oxycodone, what prescribing strategies may help in reducing the development of dependence?
A
Smaller doses at longer intervals. Use other analgesics in combination. Use modified CR formulations.
(2 to pass)
