Antibiotics Flashcards

1
Q

What class of drug is ciprofloxacin?

A

Fluroquinolone.

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2
Q

What is the mechanism of action of fluoroquinolones?

A

Blocks DNA synthesis by inhibiting bacterial topoisomerase.

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3
Q

What is the antimicrobial spectrum of ciprofloxacin?

A

Excellent gram negative coverage and moderate gram positive coverage.

Pseudomonas, Shigella, MSSA, Mycoplasma, Chlamydia, Anthrax, Legionella, Mycobacterium

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4
Q

What are the potential adverse effects of fluoroquinolones?

A

Prolonged QT, Nausea, Vomiting, Diarrhoea, Rash, Allergy, Abnormal LFTs, others…

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