Antibiotics Flashcards
1
Q
What class of drug is ciprofloxacin?
A
Fluroquinolone.
2
Q
What is the mechanism of action of fluoroquinolones?
A
Blocks DNA synthesis by inhibiting bacterial topoisomerase.
3
Q
What is the antimicrobial spectrum of ciprofloxacin?
A
Excellent gram negative coverage and moderate gram positive coverage.
Pseudomonas, Shigella, MSSA, Mycoplasma, Chlamydia, Anthrax, Legionella, Mycobacterium
4
Q
What are the potential adverse effects of fluoroquinolones?
A
Prolonged QT, Nausea, Vomiting, Diarrhoea, Rash, Allergy, Abnormal LFTs, others…