Strongyloides stercoralis Flashcards
Common name
Thread worm
A ____ Transmitted Helminth
Soil
The smallest nematode of man
Strongyloides stercoralis
Rarer than _____
hookworms
A ______ Parasite (both parasitic and Free-living)
Facultative
Usually seen among ______ patients
- elderly
- Immunocompromised
Forms: ____ are rarely seen
Eggs
Eggs will already hatch in the _________
small intestine
Possible although rare: Eggs can be recovered in severe cases; will be seen ___________ in appearance
‘chinese lantern’
____ worms will only be seen in the
free-living cycle
Male
Only _____ worms are recovered in
humans
Female
Females are capable of fertilizing their own
eggs
Parthenogenetic
MOT
arval penetration
HABITAT
small intestine
INFECTIVE STAGE
L3 filariform larva
Strongyloides stercoralis: Life Cycle
Male and Female worm undergo ______
Free-Living Phase
reproduction
Strongyloides stercoralis: Life Cycle
____ are produced by fertilized female worms
Free-Living Phase
Eggs
Strongyloides stercoralis: Life Cycle
Eggs will embryonate in the ____
Free-Living Phase
soil
Strongyloides stercoralis: Life Cycle
Eggs will hatch to release the ______
Free-Living Phase
L1 Larva
Strongyloides stercoralis: Life Cycle
L1 Larva becomes an ___ Larva, eventually, it will then become ___
Free-Living Phase
- L3
- L4
Strongyloides stercoralis: Life Cycle
Forms a new generation of adults
Free-Living Phase
L4
Strongyloides stercoralis: Life Cycle
In some unfavorable conditions, the _______ can be the infective form of filariform
Free-Living Phase
L1 Larva
Strongyloides stercoralis: Life Cycle
Presence of Infective Filariform larvae = start of the ________
Free-Living Phase
parasitic phase
Strongyloides stercoralis: Life Cycle
Infective _______ penetrates a susceptible host
Parasitic Phase
L3 Larva
Strongyloides stercoralis: Life Cycle
Once inside the host, it undergo ________
Parasitic Phase
Heart-Lung Migration
Strongyloides stercoralis: Life Cycle
After migrating, larva matures in the___________
Parasitic Phase
small intestine.
Strongyloides stercoralis: Life Cycle
Larva matures to a _______ worm in the small intestine
Parasitic Phase
female
Strongyloides stercoralis: Life Cycle
Female worm will undergo _________ to fertilize
its own eggs
Parasitic Phase
Parthenogenesis
Strongyloides stercoralis: Life Cycle
Eggs are released by the female worm to be burrowed
in the ___________
Parasitic Phase
small intestine
Strongyloides stercoralis: Life Cycle
Once in the lining, ____ will mature, and larva will be released
Parasitic Phase
Eggs
Strongyloides stercoralis: Life Cycle
Larva will be recovered in the ______
Parasitic Phase
stool
Strongyloides stercoralis: Life Cycle
L1 can possibly be _______ the small intestine
Parasitic Phase
L3 inside
Strongyloides stercoralis: Life Cycle
f there is transformation form L1 → L3, there is the possibility of _________
Parasitic Phase
autoinfection
Strongyloides stercoralis: Life Cycle
. L3 can penetrate in the ____________.
Parasitic Phase
intestinal mucosa
Strongyloides stercoralis: Life Cycle
plenty of worms and larval stages in the intestine leading to
disseminating infections
Parasitic Phase
Hyperinfection
Strongyloides stercoralis: Life Cycle
common in elderly and
immunocompromised patients which can be life-threatening
Parasitic Phase
Hyperinfection
Strongyloides stercoralis: Life Cycle
L1 Larva is more commonly recovered in ____, sometimes L3
Parasitic Phase
stool
Strongyloides stercoralis: Life Cycle
_______ is possible
Parasitic Phase
Recurrence
Strongyloides stercoralis: Life Cycle
Life cycle can last for a _____ period of time
Parasitic Phase
long
DIFFERENCES BETWEEN L1 LARVA OF HOOKWORMS AND STRONGYLOIDES SPP
short and stout
Hookworm
longer buccal cavity
Hookworm
less prominent genital
primordium
Hookworm
long and slender
Strongyloides stercoralis
short buccal cavity
Strongyloides stercoralis
prominent genital
primordium
Strongyloides stercoralis
Strongyloides stercoralis: L3 Larva
Take note of the posterior which has a _________ tail
notched or Forked
Strongyloides stercoralis: L3 Larva
Larva is _______
unsheathed
Strongyloides stercoralis: Pathology
There are many cases of strongyloides in
________
Vietnam Diarrhea/Cochin China Diarrhea
Vietnam
Strongyloides stercoralis: Pathology
Many cases seen among ______, whereas when they went back to US, they experience its disease manifestation
Vietnam Diarrhea/Cochin China Diarrhea
American soldiers
Strongyloides stercoralis: Pathology
Described to be as ________ diarrhea
Vietnam Diarrhea/Cochin China Diarrhea
Intermittent
Strongyloides stercoralis: Pathology
Due to parasites burrowing into the small intestine to lay eggs, the lining of the intestine
Honeyform appearance of intestinal mucosa
Strongyloides stercoralis: Pathology
Affecting the lungs and gastrointestinal tract
Hyperinfection and Dissemination
Strongyloides stercoralis: Pathology
Manifestations can reoccur throughout the years; since infection can last for many years
Hyperinfection and Dissemination
Strongyloides stercoralis: Pathology
Due to skin penetrating larva
Larva Currens
Strongyloides stercoralis: Pathology
Can also be found near the buttocks and
inguinal areas
Larva Currens
Strongyloides stercoralis: Pathology
attributed to the migrating larva
(heart-lung migration)
Pneumonitis
Strongyloides stercoralis: Diagnosis
Both to recover larval stages
- FECT
- Baermann Technique
Strongyloides stercoralis: Diagnosis
To obtain duodenal material
Baele’s String
Test/Enterotest
Strongyloides stercoralis: Diagnosis
recovery of larvae
Harada Mori Test
Strongyloides stercoralis: Diagnosis
Examine larva during
migration
Sputum
Strongyloides stercoralis: Diagnosis
Agar Plate Culture wherein
you will put the _____
on the blood agar plate.
Agar Plate Culture/Method
fecal matter
Strongyloides stercoralis: Diagnosis
If there is larva in the fecal
matter, the larva will tend to
move to the surface carrying
the _______ on the feces
Agar Plate Culture/Method
bacteria
Strongyloides stercoralis: Diagnosis
After incubation, Trails of
__________ on the agar plate because the bacteria are carried by the larva as it moves through the surface
Agar Plate Culture/Method
bacterial colonies
Strongyloides stercoralis: Treatment
Ivermectin with albendazole
TO DISTINGUISH HOOKWORM OR STRONGYLOIDES INFECTION
IF Abundant larval stages
in fresh specimen
Strongyloides infection
TO DISTINGUISH HOOKWORM OR STRONGYLOIDES INFECTION
IF Presence of primarily
eggs in the fresh
specimen
Hookworm infection
Strongyloides stercoralis: Epidemiology
Less _______ as compared to hookworms
common
Strongyloides stercoralis: Epidemiology
Most cases are _____
asymptomatic
Strongyloides stercoralis: Epidemiology
Disseminated and Hyperinfection are common among
________
immunocompromised
Other Strongyloides species:
Seen Central Africa
Strongyloides fulleborni
Other Strongyloides species:
“Swollen belly” sickness
Strongyloides fulleborni
Other Strongyloides species:
Can affect monkeys and humans
Strongyloides fulleborni
Other Strongyloides species:
Causing swimmer’s itch, swamp itch
Zoonotic Strongyloides
Other Strongyloides species:
Zoonotic Strongyloides:
- S. myopotami
- S. procyanis (raccons)