Other Filarial Worms Flashcards
Sheathed/Periodic Filarial worms:
○ Wuchereria bancrofti
○ Loa loa
○ Brugia malayi
Unsheathed/Non-Periodic Filarial worms:
○ Mansonella perstans
○ Mansonella ozzardi
○ Onchocerca volvulus
○ Mansonella streptocerca
majority of the microfilaria would be found in the blood of infected patients, except:
- Mansonella streptocerca (skin)
- Onchocerca volvulus (skin snips (scalp))
Loa loa
common name:
African eye worm
Loa loa
Disease manifestation:
Loaiasis
Loa loa
worms are able to migrate through _________ and _______ through the conjunctive tissue across the eyeball
tissues and eye
Loa loa
_____ of conjunctivitis and Eyelids
Edema
Loa loa
localized subcutaneous edema
Calabar/Fugitive swellings
Loa loa: Diagnosis
Presence of ______ swellings
Calabar
Loa loa: Diagnosis
Appearance of worm in the _______
conjunctiva
Loa loa: Diagnosis
Test used
Skin Test
Mansonella ozzardi
Common name
New World Filaria
Mansonella ozzardi
Disease manifestation:
Mansonellosis ozzardi
Mansonella ozzardi
found in the subcutaneous tissue in the inguinal area
Inguinal Adenopathy
Mansonella streptocerca
Formerly known as
Dipetalonema streptocerca
Mansonella streptocerca
vector
small midges belonging to Culicoides
Mansonella streptocerca
Disease manifestation
Pruritus Dermatitis with hypopigmented macules and inguinal adenopathy
Mansonella streptocerca
Where can you fine the microfilaria
skin
Mansonella streptocerca
Sheathed or unsheahted?
unsheahted
Mansonella streptocerca
____ extend up to tip
nuclei
Mansonella streptocerca
tip bent in the form of a _________
shepherd’s crook
Mansonella perstans
Formerly
Dipetalonema perstans
Mansonella perstans
Common name
Persistent Filarial worm
Mansonella perstans
Disease manifestation:
- usually benign
- calabar-like swellings
- pruritus
- hives
- fever
- Kampala or Ugandan Eye worm
Onchocerca volvulus
major cause of ______ in some parts of Africa
blindness
Onchocerca volvulus
also known as _______
river blindness
Onchocerca volvulus
found in _________
scalp (skin nodules)
Onchocerca volvulus
Adult worms can affect the eyes and may cause
__________
progressive keratitis
Onchocerca volvulus: Diagnosis
history of travel within ________ in endemic areas
6 months
Onchocerca volvulus: Diagnosis
Symptoms
itching on arms
Onchocerca volvulus: Diagnosis
Microfilaria can be identified through ________
skin biopsy
Capillaria philippinensis
Common name
Pudoc worm
Capillaria philippinensis
discovered in the _______ during the 1960’s
Ilocos Region
Capillaria philippinensis
there was a report of an epidemic of severe diarrhea in an area called _____
pudoc
Capillaria philippinensis
is one of the discoverers of this parasite
Nelia Salazar
Capillaria philippinensis
In its life cycle, there will be 2 female worms:
○ Typical Female
○ Atypical Female
Capillaria philippinensis
Mode of laying of atypical female
- Ovoviviparous (laying mature eggs)
- Larviparous
(producing larva)
Capillaria philippinensis
Mode of laying of typical female
Oviparous (laying immature eggs)
Capillaria philippinensis
The first generation female worms of Capillaria philippinensis are _______
larviparous
Capillaria philippinensis
The second generation female worms of Capillaria philippinensis are _______
oviparous
Capillaria philippinensis
the posterior part of the male worm have the _______ which is covered with sheath
spicule (chitinous)
Capillaria philippinensis
Adult worms of Capillaria philippinensis would also possess ________
secretory cells
Capillaria philippinensis
Found near the esophagus of the parasite which is found on the anterior portion of the parasite
Stichocytes (secretory cells)
Capillaria philippinensis
Row of stichocytes (secretory cells)
Stichosome (collection of stichocytes)
Capillaria philippinensis
How many eggs does a Typical Female (Oviparous) have?
8-10 eggs
Capillaria philippinensis
How many eggs does a Atypical Female (Ovoviviparous) have?
40-45 eggs
Capillaria philippinensis
with flattened
mucus plugs
Typical Female (Oviparous)