Steriods

Question 1

Steroids hormones

Answer 1

Glucocorticoids
Mineralcorticoids
Androgens

Question 2

Glucocorticoids

Answer 2

Influence carb metabolism
Cortisol most important

Hydrocortisone (cortef)

Question 3

Mineral corticoids

Answer 3

Regulate salt and water balance
Aldosterone most important
Fludrocortisone

Question 4

Androgens

Answer 4

Contribute to expression of sexual characteristics

Question 5

Negative effects of glucocorticoids

Answer 5

Osteoporosis
Muscle weakness and atrophy
Stress adaption interference
Inhibit action of growth hormone

Question 6

Prototype of glucocorticoids

Answer 6

Hydrocortisone (cortef)

Question 7

MOA of hydrocortisone

Answer 7

Produces multiple glucocorticoid and mineralocorticoid effects

Question 8

Adverse effects of hydrocortisone

Answer 8

Adrenal suppression , production of Cushing’s syndrome

Question 9

Contraindication for hydrocortisone

Answer 9

Systemic fungal infection hypersensitivity

Question 10

Dosage of hydrocortisone

Answer 10

25-30 mg bid by both
2/3 in morning (between 8 am and 9 AM)

1/3 in Afternoon dose around 4 (no later than 6 interferes with sleep)

If pt works night shift flip when they take it

Question 11

Mineralcorticoids

Answer 11

Affect renal processing of NA, K and hydrogen
Aldosterone most important

Fludrocortisone

Question 12

Teachings for steriods

Answer 12

Regular eye exam
Don’t take with alcohol and take oral doses with meals
Take any missed dose as soon as remembered
Limit sodium
Monitor sugar
Report blood or black stools mood

Question 13

What can you take your steriods with to help with flavor

Answer 13

Juice, coco cola , coffee anything strong

Question 14

Why should you not take steroid treatment and do something like the flu vaccine

Answer 14

Avoid getting flu shot because it interferes with body inflammatory response (and you need that when doing vaccines)

When you are a wk off then go get flu shot

Question 15

What teaching is important with vaccines and chronic steroid use

Answer 15

Live vaccines may be a problem consult with doc

They may get something like the flu vaccine but it interrupts the inflammatory process and it may not be as strong

Question 16

Main thing to know with steriods

Answer 16

Never stop abruptly

Question 17

two things you should always have on hand when taking steriods

Answer 17

Medical alert ID and emergency kit

Question 18

Dosage schedule for Fludrocortisone

Answer 18

PO every day 0.1-0.2
Once a day in the morning

Question 19

What is a big thing that Fludrocortisone impacts?

Answer 19

Effects potassium (hypokalemia)
And fluid balance watch for fluid retention

Question 20

If you are taking too much Fludrocortisone

Answer 20

Pt may be stimulated
Watch for wait gain, elevated BP
Psychosis ,edema CHF increase apetite . Severe insomnia and hypertension

Question 21

When should you give Fludrocortisone

Answer 21

Give daily befor 0900 to mimic body’s natural rhythm

Question 22

Important teaching with mineral corticoid/Fludrocortisone

Answer 22

Eat foods high in potassium
S/s of fluid overload
Daily weights

Question 23

Corticosteroids

Answer 23

Methylprednisolone
Dexamethasone
Prednisone

Question 24

The good of corticosteroids

Answer 24

Stop,control or reduce inflammatory response (local or systemic) in any part of the body by suppressing the immune system

Question 25

The bad of corticoid steroid use

Answer 25

Slow deterioration of the bodu

Question 26

The ugly of corticoid steriods use

Answer 26

Watch for edema , peptic ulcers, delayed wound healing , osteoporosis and infections