Hyperthyroids Medicatins Flashcards

1
Q

MOA of methimazole or propylthiouracil (PTU)

A

Inhibits the thyroid hormone synthesis

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2
Q

Adverse effects of methimazole
Propythiouracil

A

Agranulocytosis and hypothyroidism

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3
Q

Contraindications PTU methimazole

A

Allergy to thioamides, impaired liver function , pregnancy

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4
Q

What can you teach with methimazole or propythiouracil (PTU)

A

Both taken with food and do not stop taking abruptly

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5
Q

Which med can be taken during pregnancy?

A

PTU can be alright but if you can get away with not taking it you would

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6
Q

Which med is especially hard on the liver

A

PTU

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7
Q

Hyperthyroid medications

A

Methimazole
Propythiouracil (PTU)

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8
Q

If you are experiencing hypothyroidism while taking hyperthyroid medications

A

You are taking too much

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9
Q

If you are taking hyperthyroidism medications and still experiencing hyperthyroidism

A

You are taking too little

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10
Q

What should you LABS monitor with PTU

A

Thyroid and liver function tests, PT INR (clotting) & CBC

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11
Q

What do assess with PTU

A

Vital signs and weights

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12
Q

PTU pt teaching

A

Report fever sore throat, unusual bleeding (effects clotting ability)
Take medication at the same time of day w meals or snack - space doses
Signs of hypo and hyper thyroid
Do not stop abruptly

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13
Q

What two things should you avoid with hyperthyroidism

A

Decongestants and diet pills

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14
Q

Radioactive Iodine (I131)
MOA

A

destroys thyroid cells at high doses
Taking enough iodine radioactive thyroid will be destroyed (safe for other parts of the body)

Used for hyperthyroidism and for thyroid cancer

Used preop to get thyroid a lot smaller

Can be treated at home

Can also be used to shrink the size of thyroid to cut down on possibility of metastasis

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15
Q

Adverse effects of radioactive iodine I131

A

Radiation sickness, bone marrow suppression hypothyroid

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16
Q

Contraindication of radioactive iodine i131

A

Pregnancy , young children
Can damage babies thyroid

17
Q

Dosage for radioactive iodine

A

4-10 mCi orally

18
Q

What do we expect with iodine radioactive

A

Hypothyroid
But we do not want to go to fast

19
Q

Prep work before iodine radioactive

A

Private bedroom and own bath room and avoid contact with other people

20
Q

Pt teaching for iodine radioactive

A

Monitor CBC
Use private toilet / flush twice
Bathe daily and use frequent hand washin
Use disposable utensils
Sleep alone and avoide pro longed intimate contact 3-4 days
Launder linens , towels, clothes daily and seperatly
Avoid coughing and expectoration

21
Q

Other hyperthyroidism treatment

A

Strong iodine solution - non radioactive

22
Q

MOA of strong iodine solution -no radioactive

A

Reduces iodine uptake inhibits thyroid hormone production and blocks release of t3 and t4

23
Q

Adverse effect of strong iodine nonradioactive

A

Iodism

Toxicity
Looking for metallic taste of the mouth, complains of irritation inside of mouth , sore tooth and gums, mouth ulcers , can also cause swelling in upper throat area

24
Q

What can we mix iodine solution non radioactive with?

A

Juice (not so good to drink)

25
Q

Dosage of nonradioactive iodine

A

2-6 drops 3 x a day for 10 days

Same time every day

26
Q

Teachings for strong non radioactive iodine

A

Teach
Dilute meds in juice
Avoid foods high in iodine(watch for signs of under and overdosing)
Take med same time everyday
Increase fluid intake

27
Q

What is our goal/when treating hyperthyroidism?

A

More balance lab results

28
Q

What are signs of underdosing with strong iodine

A

Losing weight

29
Q

What do we monitor w strong iodine non radioactive

A

Monitor for signs of iodism
VS, weight, I&O