Lupus Flashcards
Lupus
Multisystem inflammatory autoimmune disease
Causes of lupus
Genetic influence
Hormones
Enviromental factors
Certain medications
Classifications
Systemic lupus erythematous
Discoidlupuslimited toskin
Drug induced lupus
Neonatal lupus
Discoid lupus
Round coin shape rashes
Limited to skin
Tend to be more to upper body
Risk factors
Women20-40 (child bearing yrs)
More common in African Americans, Asian Americans, Hispanics, native Americans than in whites
1 trigger of lupus
Sunlight
Other triggers of lupus
Ultraviolet light
Stress
Exposure to chemicals
Top 3 meds that cause lupus
Procainamide
Hydralazine
Quinidine
Flare ups are predictable t/f
False
Severity of SLE
Is extremely variable
Effects skin
Kidneys
Muscles
Lungs
Heart
Nervous tissue
3 main things SLE effects
Cardiopulmonary , neurologic, urinary
Cardiopulmonary s/s
Endocarditis
Myocarditis
Pericarditis
Pleural effusion
Pneumonitis
Raynaud’s phenomenon
Other s/s ofSLE
Fever of unknown origin, achy , extreme fatigue, weight loss, arthralgia
Integumentary problems SLE
Malar “butter fly “rash
Rash with sunlight exposure
Oral /nasopharyngeal ulcers
Discoid lesions
Musculoskeletal probs
Polyarthralgia with morning stiffness
Arthritis
Swan neck fingers
Ulcer deviation
Subluxation with hyperlaxity of joints
Increase risk of bone loss and fracture
Muscle pain
Cardiopulmonary s/s2
Dyspnea
Cough
Pleurisy
Raynauds
Dysrhythmias(fibrosis of SA &AV nodes)
Pericarditis
What do we get from pt every 3-6 month
A renal sample everytime they go to the doctor
Filter is damaged
And larger proteins molecules get through
Glomerulonephritis
And lupus nephritis
Also watch hypercoagability
Hyper-coagulability
Micro clots
Can effect vision and kidneys
After 2nd year of being diagnosed
Most pt may have kidney damage
If scarring and permanent damage pt can go into ESRD
Nervous system problems
Seizures
Peripheral neuropathy
Congnitive dysfunction
Psychiatric - depression and anxiety
Hematologic probs
Formation of antibodies against blood cells
Anemia
Leukopenia
Thrombocytopenia
Coagulation disorders