Staph Packet Flashcards
4 examples of Cocci?
1) Staph
2) Strep
3) Enterococcus
4) Bacilli (micrococci)
2 examples of Spore forming bacteria?
1) Bacillus
2) clostridium
2 examples of non spore forming bacteria?
1) Listeria
2) Corynebacteria
What type of cocci are staph and strep?
Pyogenic cocci
What is most important in staph and strep infections?
Role of phagocytosis/opsonization
What is negligible in staph and strep infections?
Protective immunity
what is the tissue damage from in staph/strep?
Exotoxins, bystander damage from neutrophils
What happens in a deficiency of phagocytes?
Recurrent staph and strep infections
2 examples of opsonins?
1) C-reactive protein
2) Complement
2 disease that affect neutrophil function?
1) Diabetes
2) Chronic granulomatous disease
Common cause of skin absesses?
Staph
What type of staph is coagulase +?
Staph aureus
What type of staph is coagulase -?
Staph epidermidis
Best way to get a staph epidermis infection?
Contamination of devices, implants, etc
What can be transferred by plasmids?
Antibiotic resistance
In staph infections where does bacteremia present?
Heart valves, kidneys, bones, joints
4 examples of toxins given off by Staph?
1) Enterotoxins
2) Cytolytic toxins
3) Exfoliative toxins
4) Toxic shock syndrome toxin
Staph infections involving overgrowth of normal flora? (2)
Sinusitis
Otitis media
3 types of skin/wound infections due to staph?
1) Furuncle
2) Carbuncle
3) Impetigo
What is a carbuncle>
Multiple furuncles
What causes an upper respiratory infection with Staph?
Obstruction with overgrowth of colonizing bacteria
Incubation time for food poisoning via staph?
1-6 hours
Main trait of toxic shock syndrome>
T-cell super antigen
When does bronchopneumonia show up>
secondary to viral infection and obstructive illness such as chronic pulmonary congestion, asthma, and cystic fibrosis
Where is Staph saprophytic normally found?
Normal skin, periurethral, and urethral flora
Is Staph epidermidis coagulase + or -?
-
Who is MRSA colonization most associated with?
People greater than 60 and females
How is MRSA first detected?
Clusters of abscesses or spider bites
How serious is community acquired MRSA?
Rarely associated with death, most infections are skin infections and not dangerous
Vaccine only exists for strep what?
Pneumoniae
How does Staph bind to host cells?
Fibronectin and vitronectin
Where does protein A bind?
Fc portion of immunoglobulin
Deep staph infections in immunosuppressed/debilitated?
Necrotizing pneumonia
Septicemia
How do you treat hospital aquired MRSA?
IV Vanco
