HIV/AIDS

Question 1

gag is what?

Answer 1

Core proteins

Question 2

pol is what?

Answer 2

Reverse transcriptase

Question 3

p24 is what?

Answer 3

Core protein

Screening antibodies are mode to this protein

Question 4

gp120 is what?

Answer 4

Coat protein that binds to CD4

Question 5

Increase in transmission associated with uncircumcised males due to?

Answer 5

Increased presence of dendritic cells in the foreskin

Question 6

What does HIV virus require to get into host cell

Answer 6

Co-Receptor CCR5

Question 7

Where is CCR5 expressed?

Answer 7

Monocytes and lymphocytes

Question 8

CXCR4 is expressed where?

Answer 8

T-lymphocytes

Question 9

What do activated CD8 cells produce that blocks virus uptake?

Answer 9

Chemokines RANTES
MIP-1-a
MIP-1-b

Question 10

Apoptosis of uninfected memory CD4 lymphocytes in lymph nodes resulting from what?

Answer 10

TLR-7 and TLR-8

Question 11

What is a better predictor of progression than viral load?

Answer 11

CD38

Question 12

Where do M or T forms of HIV virus show up?

Answer 12

M form in early stages’

T form in late stages