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Pathology > Bacteria 3 > Flashcards

Bacteria 3 Flashcards

1
Q

Top pathogen contributing to domestically acquired food borne illnesses?

A

Norovirus

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2
Q

Top pathogen causing food borne illness that results in hospitalization?

A

Salmonella

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3
Q

Top pathogen causing food borne illness that results in death?

A

Salmonella

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4
Q

Danger of Listeria and E.coli O157:H7?

A

Less common but cause fatal disease

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5
Q

Incubation time for ingestion of enterotoxins?

A

Hours

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6
Q

Incubation time for infection by colonizing toxigenic organisms?

A

1-3 days

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7
Q

What happens to incubation time if enteropathic bacteria invade the gut wall?

A

Extended by days-weeks

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8
Q

How do enteropathic bacteria adhere to mucosal cells?

A

Pili and flagella

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9
Q

What enterotoxin produces T-cell super antigens?

A

Staph enterotoxins

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10
Q

Which enterotoxin produces cytotoxins?

A

Shiga toxins via Shigella and E.coli O157:H7

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11
Q

Which enterotoxin produces secretagogue toxin?

A

Vibrio cholerae

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12
Q

What happens after invasion and cytolysis of enteropathic bacteria?

A

Bloody diarrhea or dysentery

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13
Q

Clinically what causes a local disease from absorbed toxin?

A

Staph

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14
Q

Clinically what causes a systemic disease from absorbed toxin?

A

Botulism, o157:H7

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15
Q

What causes secretory diarrhea?

A

Cholera

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16
Q

What causes dysentery?

A

Shigella

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17
Q

what causes systemic illness?

A

Typhoid fever

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18
Q

What is Dysentery?

A

Loose stool+ Blood + leukocytes

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19
Q

At what point does Diarrhea become dysentery?

A

Mucosal invasion

20
Q

What does Coliform mean?

A

Lactose fermenting

21
Q

What is enterotoxin e.coli?

A

Watery traveler’s diarrhea

22
Q

What is enterohemorrhagic e.coli?

A

Severe bloody colitis from o157:H7

23
Q

What is enteroaggregative E.coli?

A

Pediatric diarrhea in impoverished nations

24
Q

Source of enterohemorrhagic E.coli

A

Cattle and beef products

25
Q

What is the dose size of enterohemorrhagic E.coli?

A

Small infectious dose of

26
Q

How long does enterohemorrhagic E.coli last?

A

8 days

27
Q

What does hemolytic uremic syndrome cause?

A

Acute renal failure via obstruction of glomeruli by microthrombi

28
Q

How is Shigella spread?

A

Fecal/oral transmission, daycare centers

29
Q

Does Shigella cause bacteremia to distant organs?

A

No

30
Q

How large of a dose is needed to cause infection?

A
31
Q

Pathogenesis of Cholera?

A

Enterotoxin causes secretion of isotonic fluid

32
Q

What type of lesions does Cholera cause?

A

Non invasive

33
Q

How does the stool look in cholera?

A

Rice water

34
Q

What are the 3 types of Salmonella disease?

A

1) Typhoid
2) Enteric fever
3) Salmonella food poisoning

35
Q

What does Typhoid infect?

A

Peyer’s patches

36
Q

Most common Salmonella?

A

S. enteritidis and S. typhimurium

37
Q

Turtles are disgusting

A

They are all infected with Salmonella and pass it in feces

38
Q

Salmonella can cause what in children with sickle cell anemia?

A

Osteomyelitis and sepsis

39
Q

Does Salmonella produce enterotoxin?

A

No

40
Q

Where does Salmonella multiply?

A

Neutrophils and macrophages

41
Q

Rose spots indicative of whaT?

A

Typhoid fever

42
Q

What is associated with Guillain barre?

A

Campylobacter jejuni

43
Q

What does stool look like in Campylobacter jejune?

A

Foul smelling with blood or exudate

44
Q

Clostridium gram + or -?

A

+

45
Q

Clostridium tetani most commonly associated with what?

A

Puncture wounds

46
Q

What is the neurotoxin of Tetanus?

A

Tetanospasmin

47
Q

What do you get from raw seafood?

A

vibrio vulnificus or vibrio parahaemolyticus

Pathology (18 decks)

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