SPIROCHETES Flashcards

1
Q

Microscopes to visualize spirochetes

A

Dark field
Fluorescence
Phase Contrast

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2
Q

Loosely Coiled

A

Borrelia

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3
Q

Tightly coiled w/ corkscrew motility

A

Treponema

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4
Q

Slightly coiled w/ HOOKED ENDS

A

Leptospira

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5
Q

Spirochetes:

Arthropod vectors including lice and ticks
“stretched spirals”

A

Borellia

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6
Q

BORELLIA

Agent: Louse Borne Relapsing Fever
Vector: Human louse (Pediculus humanus)

A

B. recurrentis (EPIDEMIC)

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7
Q

BORELLIA

Agent: Tick-borne Relapsing Fever
Vector: Ornithodoros ticks

A

B. anserine, toricatae, parkeri (ENDEMIC)

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8
Q

BORELLIA

Agent: Lyme disease

A

B. burgdorferi

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9
Q

BORELLIA

B. burgdogferi is transmitted via

A

Tick vectors IXODES DAMMINI/DEER TICKS

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10
Q

Stages of LYME DISEASE

A
  1. Lesion ; Erythrema chronicum
  2. dissemination through blood
  3. neurological abnormalities; arthritis
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11
Q

TREPONEMA

Lab Diagnosis

A

Dark Field - Corkscrew motility
Levaditi silver
Serology

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12
Q

TREPONEMA

Serology:

Screening
Confirmatory

A

Screening
- VDRL
- RPR
- TRUST (Reagin Test)

Confirmatory
- FTA-ABS
- TPHA
- MHA-TP
HATTS

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13
Q

TREPONEMA

T. pallidum t. pallidum

A

Venereal Syphilis (Great pox, Evil pox, French/Italian/Spanish)

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14
Q

TREPONEMA

Primary Syphilis

A

Hard Chancre (painless and firm)

Spx: swab, aspirate

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15
Q

TREPONEMA

Secondary Syphilis

A

Condylomata lata (wart-like lesions)

Spx: serum

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16
Q

TREPONEMA

Latent Syphilis

A

Asymptomatic (+) serologic

17
Q

TREPONEMA

Tertiary syphilis

A

Neurosyphilis (Tabes dorsalis)
Gummas

Spx: CSF
Screening: VDRL
Confirmatory: FTA-ABS

18
Q

T. pallidum sub pertenue

A

Yaws/Framboise “pertenYAWS”

MOT: skin contact with inf. lesion

19
Q

T. pallidum sub endemicum

A

Bejel

MOT: mouth to mouth

20
Q

T. carateum

A

Pinta “Si cara ay gusto mag pinta”

MOT: skin contact with lesion

21
Q

TREPONEMA

Destructive lesions of gums

A

Vincent’s disease

22
Q

Tightly coiled with hooked ends

A

Leptospira

23
Q

LEPTOSPIRA

Nonpathogenic, found in water and soil

A

L. biflexa

24
Q

LEPTOSPIRA

Human and animal leptospirosis
Involves: Liver, Kidney, CNS
1 hook

A

L. interrogans

25
Q

LEPTOSPIRA

Severe form of Leptospirosis

A

Weil’s disease

26
Q

LEPTOSPIRA

Specimen 1st week

A

Blood/CSF Tissue (Acute)

27
Q

LEPTOSPIRA

Specimen 2nd week

A

Urine (Chronic)

28
Q

LEPTOSPIRA

Culture Media

A
  1. Ellinghausen-Mccoulough
  2. Fletcher’s
  3. Stuarts
29
Q

LEPTOSPIRA

Screening

A

Macroscopic Agglutination Test

serum + Ag (killed lepto) = + agglu

30
Q

LEPTOSPIRA

Confirmatory

A

Microscopic Agglutination Test

serum + Ag (live lepto) = + agglu in DF