Sleep 2 Flashcards
4 points about sleep deprivation
predominatly affects cognitive abilities
we dont make up lost sleep
following deprivation some stages of sleep predominate when we do sleep
SWS and REM sleep are most important
what was Rechtschaffen and Bergmanns experiment
sleepm deprivation in rats
metabolic rate increase, weoght loss depsite increase food intake
death after 2-3 weeks
what are 4 functions of SWS
reduced metabolic rate and blood flow
most active regions during waking show highest delta wave activity
cortex ‘shuts down’
protect from free radicals and oxidative stress
what is fatal familial insomniq
a rare genetic disorder
what happens during sleep to protect the brain
sleep drives matbolite clearance, CSF penetrates much further into brain during sleep clearing out toxic chemicals such as amyloid beta
3 functions of REM sleep
REM sleep is seen more in active phases of brain development
more prevalent in new born animals with less developed brains
REM and learning/memory
what is different for SWS and REM sleep
declarative and non-declarative memory
what is declarative memory
memeory taht can be consciously recalled- facts and evens
what is non-declarative memory
automatic learning not under conscious control- riding a bike
what is the paired associate task
used for declarative memory testing
training phase ousing word pairs presentes
SWS sleep facilitates declartive learning
what are the mechanisms during sleep that improve memory?
place cells
what are place cells
sequence of them fire along a runway- sequence is maintained and replayed during sleep
what are 4 biological rhythms
ultradian- 24 hours
circadian-24 hours
infraradian- longer than 24 hours
circannual- yearly
what controls circadian rythyms
suprachiasmatic nucleus and lesions here disrupt tiing of sleep
how does superchiasmatic woek
recieves input from retina
melanopsin containing ganglion cells are sensitive to light and connect to retina dn SCN
SCN projects to VLPA and orexin neurons of lateral hypothalamus
