SEPSIS

Question 1

life threatening organ dysfunction due to dysregulated host response to infection?

Answer 1

sepsis

Question 2

systemic effects of sepsis?

Answer 2

inflammation
temperature
WBC
respiratory rate
heart rate

Question 3

mediators that induce two effects on the patients vascular system?

name the two?

Answer 3

blood vessels dilate and capillaries become leaky

Question 4

types of organ dysfunction found in sepsis?

Answer 4

shock
septic cardiomyopathy
metabolic acidosis 
ARDs
AKI
encephalopathy
hepatic damage
blood clotting abnormalities

Question 5

sepsis diagnostic parameters?

Answer 5

SIRs

qSOFA

Question 6

site cultures?

Answer 6

urinary tract
respiratory tract
CNS, lumbar puncture
closed spaces, abdominal cavity and pleural space

Question 7

source control for blood cultures?

Answer 7

peripheral cultures from separate sites or CVC and then peripheral sample

Question 8

source control imaging?

Answer 8

radiographs
ultrasound
CT scan

Question 9

source control measures for Abx?

Answer 9

appropriateness of abx coverage

timeliness of abx coverage

Question 10

choice of crystalloid fluids in sepsis?

Answer 10

isotonic fluids

Question 11

SSC guidelines call for resuscitation fluid?

Answer 11

30 ml fluid per kg

Question 12

vasoactive therapy?

Answer 12

norepinephrine
vasopressin
epinephrine

Question 13

consider this for patients who continue with hemodynamic instability and a requirement for pressors?

Answer 13

hydrocortisone

Question 14

T/F, ascorbic acid, thiamine and hydrocortisone are or are not recommended?

Answer 14

are not