CKD PART II Flashcards
most common cause of CKD?
DM
etiologies of CKD?
high blood pressure glomerulonephritis interstitial nephritis polycystic kidney disease prolonged urinary tract obstruction vesicoureteral reflux recurrent pyelonephritis
contributing factors for CKD?
age race: blacks first gender low socioeconomic status obesity smoking
RFs for CKD?
smoker
diabetes
high blood pressure
heart disease
most common type of protein in the urine?
albumin, marker for kidney damage
how is proteinuria quantified, AKA albuminuria?
albumin to creatinine ratio
ACR: albumin/creatinine
marks risk for: progression of CKD, ESRD, mortality
chief measure of kidney function?
GFR
normal GFR values?
90-120 ml/min/1.73 m^2
how is intraglomerular pressure determined? what is unregulated?
balance of afferent and efferent blood flow
SGLT, reabsorption of glucose and Na, less Na delivered to the distal tubule
diabetes results in?
impaired auto regulatory response to fluctuations in BP
glomerular hyper filtration leads to?
glomerulosclerosis
abnormal kidney structure or function persisting greater than 3 months is called?
manifestations?
CKD
decreased GFR or persistent albuminuria
a stage of CKD which leads to death is called?
ESRD
accumulation of toxins
fluid and electrolyte abnormalities
-need life saving renal replacement therapy
CKD is staged by:
level of albuminuria
GFR
starting point for defining CKD?
<60 ml/min/1.73 m^2
